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Why do phase III clinical trials in oncology fail so often?
Amiri-Kordestani L, Fojo T. Amiri-Kordestani L, et al. J Natl Cancer Inst. 2012 Apr 18;104(8):568-9. doi: 10.1093/jnci/djs180. Epub 2012 Apr 6. J Natl Cancer Inst. 2012. PMID: 22491346 No abstract available.
Pazopanib for the treatment of breast cancer.
Amiri-Kordestani L, Tan AR, Swain SM. Amiri-Kordestani L, et al. Expert Opin Investig Drugs. 2012 Feb;21(2):217-25. doi: 10.1517/13543784.2012.652304. Epub 2012 Jan 10. Expert Opin Investig Drugs. 2012. PMID: 22233389 Review.
ANG1005 for breast cancer brain metastases: correlation between 18F-FLT-PET after first cycle and MRI in response assessment.
O'Sullivan CC, Lindenberg M, Bryla C, Patronas N, Peer CJ, Amiri-Kordestani L, Davarpanah N, Gonzalez EM, Burotto M, Choyke P, Steinberg SM, Liewehr DJ, Figg WD, Fojo T, Balasubramaniam S, Bates SE. O'Sullivan CC, et al. Breast Cancer Res Treat. 2016 Nov;160(1):51-59. doi: 10.1007/s10549-016-3972-z. Epub 2016 Sep 12. Breast Cancer Res Treat. 2016. PMID: 27620882 Free PMC article. Clinical Trial.
Phase I trial of a new schedule of romidepsin in patients with advanced cancers.
Amiri-Kordestani L, Luchenko V, Peer CJ, Ghafourian K, Reynolds J, Draper D, Frye R, Woo S, Venzon D, Wright J, Skarulis M, Figg WD, Fojo T, Bates SE, Piekarz RL. Amiri-Kordestani L, et al. Clin Cancer Res. 2013 Aug 15;19(16):4499-507. doi: 10.1158/1078-0432.CCR-13-0095. Epub 2013 Jun 11. Clin Cancer Res. 2013. PMID: 23757352 Free PMC article. Clinical Trial.
The TRAIL receptor agonist drozitumab targets basal B triple-negative breast cancer cells that express vimentin and Axl.
Dine JL, O'Sullivan CC, Voeller D, Greer YE, Chavez KJ, Conway CM, Sinclair S, Stone B, Amiri-Kordestani L, Merchant AS, Hewitt SM, Steinberg SM, Swain SM, Lipkowitz S. Dine JL, et al. Breast Cancer Res Treat. 2016 Jan;155(2):235-51. doi: 10.1007/s10549-015-3673-z. Epub 2016 Jan 12. Breast Cancer Res Treat. 2016. PMID: 26759246 Free PMC article.
91 results