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Tuning Selectivity in CalA Lipase: Beyond Tunnel Engineering.
Alejaldre L, Lemay-St-Denis C, Pelletier JN, Quaglia D. Alejaldre L, et al. Among authors: pelletier jn. Biochemistry. 2023 Jan 17;62(2):396-409. doi: 10.1021/acs.biochem.2c00513. Epub 2022 Dec 29. Biochemistry. 2023. PMID: 36580299 Free PMC article.
Integron-Associated DfrB4, a Previously Uncharacterized Member of the Trimethoprim-Resistant Dihydrofolate Reductase B Family, Is a Clinically Identified Emergent Source of Antibiotic Resistance.
Toulouse JL, Edens TJ, Alejaldre L, Manges AR, Pelletier JN. Toulouse JL, et al. Among authors: pelletier jn. Antimicrob Agents Chemother. 2017 Apr 24;61(5):e02665-16. doi: 10.1128/AAC.02665-16. Print 2017 May. Antimicrob Agents Chemother. 2017. PMID: 28242670 Free PMC article.
Dual-Target Inhibitors of the Folate Pathway Inhibit Intrinsically Trimethoprim-Resistant DfrB Dihydrofolate Reductases.
Toulouse JL, Shi G, Lemay-St-Denis C, Ebert MCCJC, Deon D, Gagnon M, Ruediger E, Saint-Jacques K, Forge D, Vanden Eynde JJ, Marinier A, Ji X, Pelletier JN. Toulouse JL, et al. Among authors: pelletier jn. ACS Med Chem Lett. 2020 Sep 28;11(11):2261-2267. doi: 10.1021/acsmedchemlett.0c00393. eCollection 2020 Nov 12. ACS Med Chem Lett. 2020. PMID: 33214838 Free PMC article.
Development of sulfahydantoin derivatives as β-lactamase inhibitors.
Paquet-Côté PA, Alejaldre L, Lapointe Verreault C, Gobeil SMC, Lamoureux R, Bédard L, Normandeau CO, Lemay-St-Denis C, Pelletier JN, Voyer N. Paquet-Côté PA, et al. Among authors: pelletier jn. Bioorg Med Chem Lett. 2021 Mar 1;35:127781. doi: 10.1016/j.bmcl.2021.127781. Epub 2021 Jan 8. Bioorg Med Chem Lett. 2021. PMID: 33422604
91 results