Cheng Y - Search Results

1

Novel Small-Molecule PD-L1 Inhibitor Induces PD-L1 Internalization and Optimizes the Immune Microenvironment.

Sun C, Yin M, Cheng Y, Kuang Z, Liu X, Wang G, Wang X, Yuan K, Min W, Dong J, Hou Y, Hu L, Zhang G, Pei W, Wang L, Sun Y, Yu X, Xiao Y, Deng H, Yang P. Sun C, et al. Among authors: cheng y. J Med Chem. 2023 Feb 9;66(3):2064-2083. doi: 10.1021/acs.jmedchem.2c01801. Epub 2022 Dec 29. J Med Chem. 2023. PMID: 36579489

2

Discovery of Small-Molecule Inhibitors of the PD-1/PD-L1 Axis That Promote PD-L1 Internalization and Degradation.

Wang T, Cai S, Cheng Y, Zhang W, Wang M, Sun H, Guo B, Li Z, Xiao Y, Jiang S. Wang T, et al. Among authors: cheng y. J Med Chem. 2022 Mar 10;65(5):3879-3893. doi: 10.1021/acs.jmedchem.1c01682. Epub 2022 Feb 21. J Med Chem. 2022. PMID: 35188766

3

Design, Synthesis, and Evaluation of PD-1/PD-L1 Antagonists Bearing a Benzamide Scaffold.

Lu L, Qi Z, Wang T, Zhang X, Zhang K, Wang K, Cheng Y, Xiao Y, Li Z, Jiang S. Lu L, et al. Among authors: cheng y. ACS Med Chem Lett. 2022 Mar 29;13(4):586-592. doi: 10.1021/acsmedchemlett.1c00646. eCollection 2022 Apr 14. ACS Med Chem Lett. 2022. PMID: 35450381 Free PMC article.

4

Novel phthalimides regulating PD-1/PD-L1 interaction as potential immunotherapy agents.

Sun C, Cheng Y, Liu X, Wang G, Min W, Wang X, Yuan K, Hou Y, Li J, Zhang H, Dong H, Wang L, Lou C, Sun Y, Yu X, Deng H, Xiao Y, Yang P. Sun C, et al. Among authors: cheng y. Acta Pharm Sin B. 2022 Dec;12(12):4446-4457. doi: 10.1016/j.apsb.2022.04.007. Epub 2022 Apr 16. Acta Pharm Sin B. 2022. PMID: 36561991 Free PMC article.

5

Discovery and Crystallography Study of Novel Biphenyl Ether and Oxadiazole Thioether (Non-Arylmethylamine)-Based Small-Molecule PD-1/PD-L1 Inhibitors as Immunotherapeutic Agents.

Liu J, Cheng Y, Yuan L, Liu T, Ruan Y, Ren Y, Li L, Jiang S, Xiao Y, Chen J. Liu J, et al. Among authors: cheng y. J Med Chem. 2023 Sep 28;66(18):13172-13188. doi: 10.1021/acs.jmedchem.3c01141. Epub 2023 Sep 6. J Med Chem. 2023. PMID: 37674362

6

LFG-500 inhibits the invasion of cancer cells via down-regulation of PI3K/AKT/NF-κB signaling pathway.

Li C, Li F, Zhao K, Yao J, Cheng Y, Zhao L, Li Z, Lu N, Guo Q. Li C, et al. Among authors: cheng y. PLoS One. 2014 Mar 11;9(3):e91332. doi: 10.1371/journal.pone.0091332. eCollection 2014. PLoS One. 2014. PMID: 24618693 Free PMC article.

7

Oroxylin A inhibits hypoxia-induced invasion and migration of MCF-7 cells by suppressing the Notch pathway.

Cheng Y, Zhao K, Li G, Yao J, Dai Q, Hui H, Li Z, Guo Q, Lu N. Cheng Y, et al. Anticancer Drugs. 2014 Aug;25(7):778-89. doi: 10.1097/CAD.0000000000000103. Anticancer Drugs. 2014. PMID: 24637576

8

Photonic crystal microcapsules for label-free multiplex detection.

Ye B, Ding H, Cheng Y, Gu H, Zhao Y, Xie Z, Gu Z. Ye B, et al. Among authors: cheng y. Adv Mater. 2014 May 28;26(20):3270-4. doi: 10.1002/adma.201305035. Epub 2014 Feb 18. Adv Mater. 2014. PMID: 24550084

9

Robust Jumping Actuator with a Shrimp-Shell Architecture.

Yu K, Ji X, Yuan T, Cheng Y, Li J, Hu X, Liu Z, Zhou X, Fang L. Yu K, et al. Among authors: cheng y. Adv Mater. 2021 Nov;33(44):e2104558. doi: 10.1002/adma.202104558. Epub 2021 Sep 13. Adv Mater. 2021. PMID: 34514641

10

Bioinspired Helical Microfibers from Microfluidics.

Yu Y, Fu F, Shang L, Cheng Y, Gu Z, Zhao Y. Yu Y, et al. Among authors: cheng y. Adv Mater. 2017 May;29(18). doi: 10.1002/adma.201605765. Epub 2017 Mar 7. Adv Mater. 2017. PMID: 28266759

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