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LPA receptor 1 (LPAR1) is a novel interaction partner of Filamin A that promotes Filamin A phosphorylation, MRTF-A transcriptional activity and oncogene-induced senescence.
Konopa A, Meier MA, Franz MJ, Bernardinelli E, Voegele AL, Atreya R, Ribback S, Roessler S, Aigner A, Singer K, Singer S, Sarikas A, Muehlich S. Konopa A, et al. Among authors: aigner a. Oncogenesis. 2022 Dec 28;11(1):69. doi: 10.1038/s41389-022-00445-z. Oncogenesis. 2022. PMID: 36577757 Free PMC article.
Depletion of the transcriptional coactivators megakaryoblastic leukaemia 1 and 2 abolishes hepatocellular carcinoma xenograft growth by inducing oncogene-induced senescence.
Hampl V, Martin C, Aigner A, Hoebel S, Singer S, Frank N, Sarikas A, Ebert O, Prywes R, Gudermann T, Muehlich S. Hampl V, et al. Among authors: aigner a. EMBO Mol Med. 2013 Sep;5(9):1367-82. doi: 10.1002/emmm.201202406. Epub 2013 Jul 29. EMBO Mol Med. 2013. PMID: 23853104 Free PMC article.
Tetraspanin 5 (TSPAN5), a Novel Gatekeeper of the Tumor Suppressor DLC1 and Myocardin-Related Transcription Factors (MRTFs), Controls HCC Growth and Senescence.
Schreyer L, Mittermeier C, Franz MJ, Meier MA, Martin DE, Maier KC, Huebner K, Schneider-Stock R, Singer S, Holzer K, Fischer D, Ribback S, Liebl B, Gudermann T, Aigner A, Muehlich S. Schreyer L, et al. Among authors: aigner a. Cancers (Basel). 2021 Oct 26;13(21):5373. doi: 10.3390/cancers13215373. Cancers (Basel). 2021. PMID: 34771537 Free PMC article.
Exploring the MIR143-UPAR Axis for the Inhibition of Human Prostate Cancer Cells In Vitro and In Vivo.
Wach S, Brandl M, Borchardt H, Weigelt K, Lukat S, Nolte E, Al-Janabi O, Hart M, Grässer F, Giedl J, Jung R, Stöhr R, Hartmann A, Lieb V, Höbel S, Peters A, Stäubert C, Wullich B, Taubert H, Aigner A. Wach S, et al. Among authors: aigner a. Mol Ther Nucleic Acids. 2019 Jun 7;16:272-283. doi: 10.1016/j.omtn.2019.02.020. Epub 2019 Feb 27. Mol Ther Nucleic Acids. 2019. PMID: 30933831 Free PMC article.
305 results