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HOXA9 forms a repressive complex with nuclear matrix-associated protein SAFB to maintain acute myeloid leukemia.
Agrawal-Singh S, Bagri J, Giotopoulos G, Azazi DMA, Horton SJ, Lopez CK, Anand S, Bach AS, Stedham F, Antrobus R, Houghton JW, Vassiliou GS, Sasca D, Yun H, Whetton AD, Huntly BJP. Agrawal-Singh S, et al. Among authors: huntly bjp. Blood. 2023 Apr 6;141(14):1737-1754. doi: 10.1182/blood.2022016528. Blood. 2023. PMID: 36577137 Free PMC article.
Regulatory T-Cell Response to Low-Dose Interleukin-2 in Ischemic Heart Disease.
Zhao TX, Sriranjan RS, Tuong ZK, Lu Y, Sage AP, Nus M, Hubsch A, Kaloyirou F, Vamvaka E, Helmy J, Kostapanos M, Jalaludeen N, Klatzmann D, Tedgui A, Rudd JHF, Horton SJ, Huntly BJP, Hoole SP, Bond SP, Clatworthy MR, Cheriyan J, Mallat Z. Zhao TX, et al. Among authors: huntly bjp. NEJM Evid. 2022 Jan;1(1):EVIDoa2100009. doi: 10.1056/EVIDoa2100009. Epub 2021 Nov 22. NEJM Evid. 2022. PMID: 38319239 Clinical Trial.
ESMO-Magnitude of Clinical Benefit Scale for haematological malignancies (ESMO-MCBS:H) version 1.0.
Kiesewetter B, Dafni U, de Vries EGE, Barriuso J, Curigliano G, González-Calle V, Galotti M, Gyawali B, Huntly BJP, Jäger U, Latino NJ, Malcovati L, Oosting SF, Ossenkoppele G, Piccart M, Raderer M, Scarfò L, Trapani D, Zielinski CC, Wester R, Zygoura P, Macintyre E, Cherny NI; ESMO-MCBS Working Group and Extended Working Group. Kiesewetter B, et al. Among authors: huntly bjp. Ann Oncol. 2023 Sep;34(9):734-771. doi: 10.1016/j.annonc.2023.06.002. Epub 2023 Jun 19. Ann Oncol. 2023. PMID: 37343663
Preleukemic single-cell landscapes reveal mutation-specific mechanisms and gene programs predictive of AML patient outcomes.
Isobe T, Kucinski I, Barile M, Wang X, Hannah R, Bastos HP, Chabra S, Vijayabaskar MS, Sturgess KHM, Williams MJ, Giotopoulos G, Marando L, Li J, Rak J, Gozdecka M, Prins D, Shepherd MS, Watcham S, Green AR, Kent DG, Vassiliou GS, Huntly BJP, Wilson NK, Göttgens B. Isobe T, et al. Among authors: huntly bjp. Cell Genom. 2023 Oct 27;3(12):100426. doi: 10.1016/j.xgen.2023.100426. eCollection 2023 Dec 13. Cell Genom. 2023. PMID: 38116120 Free PMC article.
A guide to epigenetics in leukaemia stem cells.
Agrawal-Singh S, Bagri J, Sakakini N, Huntly BJP. Agrawal-Singh S, et al. Among authors: huntly bjp. Mol Oncol. 2023 Dec;17(12):2493-2506. doi: 10.1002/1878-0261.13544. Epub 2023 Nov 2. Mol Oncol. 2023. PMID: 37872885 Free PMC article. Review.
Distinct and targetable role of calcium-sensing receptor in leukaemia.
Pereira RS, Kumar R, Cais A, Paulini L, Kahler A, Bravo J, Minciacchi VR, Krack T, Kowarz E, Zanetti C, Godavarthy PS, Hoeller F, Llavona P, Stark T, Tascher G, Nowak D, Meduri E, Huntly BJP, Münch C, Pampaloni F, Marschalek R, Krause DS. Pereira RS, et al. Among authors: huntly bjp. Nat Commun. 2023 Oct 6;14(1):6242. doi: 10.1038/s41467-023-41770-0. Nat Commun. 2023. PMID: 37802982 Free PMC article.
In vivo screening characterizes chromatin factor functions during normal and malignant hematopoiesis.
Lara-Astiaso D, Goñi-Salaverri A, Mendieta-Esteban J, Narayan N, Del Valle C, Gross T, Giotopoulos G, Beinortas T, Navarro-Alonso M, Aguado-Alvaro LP, Zazpe J, Marchese F, Torrea N, Calvo IA, Lopez CK, Alignani D, Lopez A, Saez B, Taylor-King JP, Prosper F, Fortelny N, Huntly BJP. Lara-Astiaso D, et al. Among authors: huntly bjp. Nat Genet. 2023 Sep;55(9):1542-1554. doi: 10.1038/s41588-023-01471-2. Epub 2023 Aug 14. Nat Genet. 2023. PMID: 37580596 Free PMC article.
Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death.
Woodley K, Dillingh LS, Giotopoulos G, Madrigal P, Rattigan KM, Philippe C, Dembitz V, Magee AMS, Asby R, van de Lagemaat LN, Mapperley C, James SC, Prehn JHM, Tzelepis K, Rouault-Pierre K, Vassiliou GS, Kranc KR, Helgason GV, Huntly BJP, Gallipoli P. Woodley K, et al. Among authors: huntly bjp. Nat Commun. 2023 Apr 14;14(1):2132. doi: 10.1038/s41467-023-37652-0. Nat Commun. 2023. PMID: 37059720 Free PMC article.
95 results