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Increased numbers of pre-operative circulating monocytes predict risk of developing cardiac surgery-associated acute kidney injury in conditions requiring cardio pulmonary bypass.
Okadome Y, Morinaga J, Yamanouchi Y, Matsunaga E, Fukami H, Kadomatsu T, Horiguchi H, Sato M, Sugizaki T, Hayata M, Sakaguchi T, Hirayama R, Ishimura T, Kuwabara T, Usuku K, Yamamoto T, Mukoyama M, Suzuki R, Fukui T, Oike Y. Okadome Y, et al. Among authors: morinaga j. Clin Exp Nephrol. 2023 Apr;27(4):329-339. doi: 10.1007/s10157-022-02313-x. Epub 2022 Dec 28. Clin Exp Nephrol. 2023. PMID: 36576647
In vivo contribution of serine proteases to the proteolytic activation of γENaC in aldosterone-infused rats.
Uchimura K, Kakizoe Y, Onoue T, Hayata M, Morinaga J, Yamazoe R, Ueda M, Mizumoto T, Adachi M, Miyoshi T, Shiraishi N, Sakai Y, Tomita K, Kitamura K. Uchimura K, et al. Among authors: morinaga j. Am J Physiol Renal Physiol. 2012 Oct;303(7):F939-43. doi: 10.1152/ajprenal.00705.2011. Epub 2012 Jul 25. Am J Physiol Renal Physiol. 2012. PMID: 22832922 Free article.
Effect of a serine protease inhibitor on the progression of chronic renal failure.
Hayata M, Kakizoe Y, Uchimura K, Morinaga J, Yamazoe R, Mizumoto T, Onoue T, Ueda M, Shiraishi N, Adachi M, Miyoshi T, Sakai Y, Tomita K, Kitamura K. Hayata M, et al. Among authors: morinaga j. Am J Physiol Renal Physiol. 2012 Oct 15;303(8):F1126-35. doi: 10.1152/ajprenal.00706.2011. Epub 2012 Jul 25. Am J Physiol Renal Physiol. 2012. PMID: 22832926 Free article.
The antifibrotic effect of a serine protease inhibitor in the kidney.
Morinaga J, Kakizoe Y, Miyoshi T, Onoue T, Ueda M, Mizumoto T, Yamazoe R, Uchimura K, Hayata M, Shiraishi N, Adachi M, Sakai Y, Tomita K, Kitamura K. Morinaga J, et al. Am J Physiol Renal Physiol. 2013 Jul 15;305(2):F173-81. doi: 10.1152/ajprenal.00586.2012. Epub 2013 May 22. Am J Physiol Renal Physiol. 2013. PMID: 23698112 Free article.
ANGPTL2 increases bone metastasis of breast cancer cells through enhancing CXCR4 signaling.
Masuda T, Endo M, Yamamoto Y, Odagiri H, Kadomatsu T, Nakamura T, Tanoue H, Ito H, Yugami M, Miyata K, Morinaga J, Horiguchi H, Motokawa I, Terada K, Morioka MS, Manabe I, Iwase H, Mizuta H, Oike Y. Masuda T, et al. Among authors: morinaga j. Sci Rep. 2015 Mar 16;5:9170. doi: 10.1038/srep09170. Sci Rep. 2015. PMID: 25773070 Free PMC article.
Angiopoietin-like protein 2 increases renal fibrosis by accelerating transforming growth factor-β signaling in chronic kidney disease.
Morinaga J, Kadomatsu T, Miyata K, Endo M, Terada K, Tian Z, Sugizaki T, Tanigawa H, Zhao J, Zhu S, Sato M, Araki K, Iyama K, Tomita K, Mukoyama M, Tomita K, Kitamura K, Oike Y. Morinaga J, et al. Kidney Int. 2016 Feb;89(2):327-41. doi: 10.1016/j.kint.2015.12.021. Epub 2016 Jan 1. Kidney Int. 2016. PMID: 26806834 Free article.
Combination therapy with renin-angiotensin-aldosterone system inhibitor telmisartan and serine protease inhibitor camostat mesilate provides further renoprotection in a rat chronic kidney disease model.
Narita Y, Ueda M, Uchimura K, Kakizoe Y, Miyasato Y, Mizumoto T, Morinaga J, Hayata M, Nakagawa T, Adachi M, Miyoshi T, Sakai Y, Kadowaki D, Hirata S, Mukoyama M, Kitamura K. Narita Y, et al. Among authors: morinaga j. J Pharmacol Sci. 2016 Feb;130(2):110-6. doi: 10.1016/j.jphs.2016.01.003. Epub 2016 Jan 20. J Pharmacol Sci. 2016. PMID: 26887332 Free article.
Mice Deficient in Angiopoietin-like Protein 2 (Angptl2) Gene Show Increased Susceptibility to Bacterial Infection Due to Attenuated Macrophage Activity.
Yugami M, Odagiri H, Endo M, Tsutsuki H, Fujii S, Kadomatsu T, Masuda T, Miyata K, Terada K, Tanoue H, Ito H, Morinaga J, Horiguchi H, Sugizaki T, Akaike T, Gotoh T, Takai T, Sawa T, Mizuta H, Oike Y. Yugami M, et al. Among authors: morinaga j. J Biol Chem. 2016 Sep 2;291(36):18843-52. doi: 10.1074/jbc.M116.720870. Epub 2016 Jul 11. J Biol Chem. 2016. PMID: 27402837 Free PMC article.
Interstitial pneumonia induced by bleomycin treatment is exacerbated in Angptl2-deficient mice.
Motokawa I, Endo M, Terada K, Horiguchi H, Miyata K, Kadomatsu T, Morinaga J, Sugizaki T, Ito T, Araki K, Morioka MS, Manabe I, Samukawa T, Watanabe M, Inoue H, Oike Y. Motokawa I, et al. Among authors: morinaga j. Am J Physiol Lung Cell Mol Physiol. 2016 Oct 1;311(4):L704-L713. doi: 10.1152/ajplung.00005.2016. Epub 2016 Aug 19. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 27542805 Free article.
75 results