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Ghrelin receptor signaling in health and disease: a biased view.
Gross JD, Zhou Y, Barak LS, Caron MG. Gross JD, et al. Among authors: barak ls. Trends Endocrinol Metab. 2023 Feb;34(2):106-118. doi: 10.1016/j.tem.2022.12.001. Epub 2022 Dec 24. Trends Endocrinol Metab. 2023. PMID: 36567228 Free PMC article. Review.
Biased Allosteric Modulators: New Frontiers in GPCR Drug Discovery.
Slosky LM, Caron MG, Barak LS. Slosky LM, et al. Among authors: barak ls. Trends Pharmacol Sci. 2021 Apr;42(4):283-299. doi: 10.1016/j.tips.2020.12.005. Epub 2021 Feb 10. Trends Pharmacol Sci. 2021. PMID: 33581873 Free PMC article. Review.
Discovery of ML314, a Brain Penetrant Non-Peptidic β-Arrestin Biased Agonist of the Neurotensin NTR1 Receptor.
Peddibhotla S, Hedrick MP, Hershberger P, Maloney PR, Li Y, Milewski M, Gosalia P, Gray W, Mehta A, Sugarman E, Hood B, Suyama E, Nguyen K, Heynen-Genel S, Vasile S, Salaniwal S, Stonich D, Su Y, Mangravita-Novo A, Vicchiarelli M, Roth GP, Smith LH, Chung TD, Hanson GR, Thomas JB, Caron MG, Barak LS, Pinkerton AB. Peddibhotla S, et al. Among authors: barak ls. ACS Med Chem Lett. 2013 Jul 20;4(9):846-851. doi: 10.1021/ml400176n. ACS Med Chem Lett. 2013. PMID: 24611085 Free PMC article.
G Protein and β-arrestin signaling bias at the ghrelin receptor.
Evron T, Peterson SM, Urs NM, Bai Y, Rochelle LK, Caron MG, Barak LS. Evron T, et al. Among authors: barak ls. J Biol Chem. 2014 Nov 28;289(48):33442-55. doi: 10.1074/jbc.M114.581397. Epub 2014 Sep 26. J Biol Chem. 2014. PMID: 25261469 Free PMC article.
137 results