Tikhomirov AS - Search Results

1

Design, Synthesis and In Vitro Investigation of Cabozantinib-Based PROTACs to Target c-Met Kinase.

Sachkova AA, Andreeva DV, Tikhomirov AS, Scherbakov AM, Salnikova DI, Sorokin DV, Bogdanov FB, Rysina YD, Shchekotikhin AE, Shchegravina ES, Fedorov AY. Sachkova AA, et al. Among authors: tikhomirov as. Pharmaceutics. 2022 Dec 16;14(12):2829. doi: 10.3390/pharmaceutics14122829. Pharmaceutics. 2022. PMID: 36559322 Free PMC article.

2

Advances in the Discovery of Anthraquinone-Based Anticancer Agents.

Tikhomirov AS, Shtil AA, Shchekotikhin AE. Tikhomirov AS, et al. Recent Pat Anticancer Drug Discov. 2018;13(2):159-183. doi: 10.2174/1574892813666171206123114. Recent Pat Anticancer Drug Discov. 2018. PMID: 29210664 Review.

3

Heterocyclic ring expansion yields anthraquinone derivatives potent against multidrug resistant tumor cells.

Tikhomirov AS, Tsvetkov VB, Volodina YL, Litvinova VA, Andreeva DV, Dezhenkova LG, Kaluzhny DN, Treshalin ID, Shtil AA, Shchekotikhin AE. Tikhomirov AS, et al. Bioorg Chem. 2022 Oct;127:105925. doi: 10.1016/j.bioorg.2022.105925. Epub 2022 Jun 4. Bioorg Chem. 2022. PMID: 35728293

4

Tri-armed ligands of G-quadruplex on heteroarene-fused anthraquinone scaffolds: Design, synthesis and pre-screening of biological properties.

Tikhomirov AS, Tsvetkov VB, Kaluzhny DN, Volodina YL, Zatonsky GV, Schols D, Shchekotikhin AE. Tikhomirov AS, et al. Eur J Med Chem. 2018 Nov 5;159:59-73. doi: 10.1016/j.ejmech.2018.09.054. Epub 2018 Sep 22. Eur J Med Chem. 2018. PMID: 30268824

5

Amides of pyrrole- and thiophene-fused anthraquinone derivatives: A role of the heterocyclic core in antitumor properties.

Tikhomirov AS, Litvinova VA, Andreeva DV, Tsvetkov VB, Dezhenkova LG, Volodina YL, Kaluzhny DN, Treshalin ID, Schols D, Ramonova AA, Moisenovich MM, Shtil AA, Shchekotikhin AE. Tikhomirov AS, et al. Eur J Med Chem. 2020 Aug 1;199:112294. doi: 10.1016/j.ejmech.2020.112294. Epub 2020 May 6. Eur J Med Chem. 2020. PMID: 32428792

6

Thiophene-2-carboxamide derivatives of anthraquinone: A new potent antitumor chemotype.

Volodina YL, Tikhomirov AS, Dezhenkova LG, Ramonova AA, Kononova AV, Andreeva DV, Kaluzhny DN, Schols D, Moisenovich MM, Shchekotikhin AE, Shtil AA. Volodina YL, et al. Among authors: tikhomirov as. Eur J Med Chem. 2021 Oct 5;221:113521. doi: 10.1016/j.ejmech.2021.113521. Epub 2021 May 24. Eur J Med Chem. 2021. PMID: 34082225

7

Computational and Biophysical Characterization of Heterocyclic Derivatives of Anthraquinone against Human Aurora Kinase A.

Singh M, Haque MA, Tikhomirov AS, Shchekotikhin AE, Das U, Kaur P. Singh M, et al. Among authors: tikhomirov as. ACS Omega. 2022 Oct 27;7(44):39603-39618. doi: 10.1021/acsomega.2c00740. eCollection 2022 Nov 8. ACS Omega. 2022. PMID: 36385832 Free PMC article.

8

Semi-Synthetic Derivatives of Heliomycin with an Antiproliferative Potency.

Nadysev GY, Tikhomirov AS, Dezhenkova LG, Shchekotikhin AE. Nadysev GY, et al. Among authors: tikhomirov as. Recent Pat Anticancer Drug Discov. 2018 Oct 3;13(4):469-472. doi: 10.2174/1574892813666180723150542. Recent Pat Anticancer Drug Discov. 2018. PMID: 30039764 Review.

9

Engagement with tNOX (ENOX2) to Inhibit SIRT1 and Activate p53-Dependent and -Independent Apoptotic Pathways by Novel 4,11-Diaminoanthra[2,3-b]furan-5,10-diones in Hepatocellular Carcinoma Cells.

Lin CY, Islam A, Su CJ, Tikhomirov AS, Shchekotikhin AE, Chuang SM, Chueh PJ, Chen YL. Lin CY, et al. Among authors: tikhomirov as. Cancers (Basel). 2019 Mar 24;11(3):420. doi: 10.3390/cancers11030420. Cancers (Basel). 2019. PMID: 30909652 Free PMC article.

10

Experimental Evaluation of Anticancer Efficiency and Acute Toxicity of Anthrafuran for Oral Administration.

Shchekotikhin AE, Treshalina HM, Treshchalin MI, Pereverzeva ER, Isakova HB, Tikhomirov AS. Shchekotikhin AE, et al. Among authors: tikhomirov as. Pharmaceuticals (Basel). 2020 Apr 28;13(5):81. doi: 10.3390/ph13050081. Pharmaceuticals (Basel). 2020. PMID: 32353946 Free PMC article.

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