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A Broad Spectrum Antiparasitic Activity of Organotin (IV) Derivatives and Its Untargeted Proteomic Profiling Using Leishmania donovani.
Hayat O, Ullah N, Sirajuddin M, Giardini MA, Nguyen JV, Francisco KR, Liu LJ, Sun YU, Maurya S, McGrosso D, Gonzalez DJ, Caffrey CR, Debnath A, Siqueira-Neto JL. Hayat O, et al. Among authors: francisco kr. Pathogens. 2022 Nov 26;11(12):1424. doi: 10.3390/pathogens11121424. Pathogens. 2022. PMID: 36558759 Free PMC article.
Microtubule-Stabilizing 1,2,4-Triazolo[1,5-a]pyrimidines as Candidate Therapeutics for Neurodegenerative Disease: Matched Molecular Pair Analyses and Computational Studies Reveal New Structure-Activity Insights.
Alle T, Varricchio C, Yao Y, Lucero B, Nzou G, Demuro S, Muench M, Vuong KD, Oukoloff K, Cornec AS, Francisco KR, Caffrey CR, Lee VM, Smith AB 3rd, Brancale A, Brunden KR, Ballatore C. Alle T, et al. Among authors: francisco kr. J Med Chem. 2023 Jan 12;66(1):435-459. doi: 10.1021/acs.jmedchem.2c01411. Epub 2022 Dec 19. J Med Chem. 2023. PMID: 36534051 Free PMC article.
Structure-activity relationship of dibenzylideneacetone analogs against the neglected disease pathogen, Trypanosoma brucei.
Francisco KR, Monti L, Yang W, Park H, Liu LJ, Watkins K, Amarasinghe DK, Nalli M, Roberto Polaquini C, Regasini LO, Eduardo Miller Crotti A, Silvestri R, Guidi Magalhães L, Caffrey CR. Francisco KR, et al. Bioorg Med Chem Lett. 2023 Feb 1;81:129123. doi: 10.1016/j.bmcl.2023.129123. Epub 2023 Jan 3. Bioorg Med Chem Lett. 2023. PMID: 36608774 Free PMC article.
Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein-Protein Interaction Inhibitors.
Francisco KR, Bruystens J, Varricchio C, McCurdy S, Wu J, Lopez-Ramirez MA, Ginsberg M, Caffrey CR, Brancale A, Gingras AR, Hixon MS, Ballatore C. Francisco KR, et al. ACS Pharmacol Transl Sci. 2023 Oct 9;6(11):1651-1658. doi: 10.1021/acsptsci.3c00156. eCollection 2023 Nov 10. ACS Pharmacol Transl Sci. 2023. PMID: 37974623 Free article.
32 results