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Sphingosine as a New Antifungal Agent against Candida and Aspergillus spp.
Hashemi Arani F, Kadow S, Kramer M, Keitsch S, Kirchhoff L, Schumacher F, Kleuser B, Rath PM, Gulbins E, Carpinteiro A. Hashemi Arani F, et al. Among authors: keitsch s. Int J Mol Sci. 2022 Dec 7;23(24):15510. doi: 10.3390/ijms232415510. Int J Mol Sci. 2022. PMID: 36555152 Free PMC article.
[Proapoptotic antibodies as new therapeutic agents for tumor treatment].
Schenck M, Börgermann C, vom Dorp F, Groneberg M, Busch Y, Carpinteiro A, Wilker B, Keitsch S, Moyrer S, Schmid KW, Stuschke M, Rübben H, Gulbins E. Schenck M, et al. Among authors: keitsch s. Urologe A. 2007 Sep;46(9):1262-5. doi: 10.1007/s00120-007-1385-7. Urologe A. 2007. PMID: 17598083 German.
Regulation of hematogenous tumor metastasis by acid sphingomyelinase.
Carpinteiro A, Becker KA, Japtok L, Hessler G, Keitsch S, Požgajovà M, Schmid KW, Adams C, Müller S, Kleuser B, Edwards MJ, Grassmé H, Helfrich I, Gulbins E. Carpinteiro A, et al. Among authors: keitsch s. EMBO Mol Med. 2015 Jun;7(6):714-34. doi: 10.15252/emmm.201404571. EMBO Mol Med. 2015. PMID: 25851537 Free PMC article.
Staphylococcus aureus Alpha-Toxin Disrupts Endothelial-Cell Tight Junctions via Acid Sphingomyelinase and Ceramide.
Becker KA, Fahsel B, Kemper H, Mayeres J, Li C, Wilker B, Keitsch S, Soddemann M, Sehl C, Kohnen M, Edwards MJ, Grassmé H, Caldwell CC, Seitz A, Fraunholz M, Gulbins E. Becker KA, et al. Among authors: keitsch s. Infect Immun. 2017 Dec 19;86(1):e00606-17. doi: 10.1128/IAI.00606-17. Print 2018 Jan. Infect Immun. 2017. PMID: 29084896 Free PMC article.
Inhibition of PI-3-K and AKT Amplifies Kv1.3 Inhibitor-Induced Death of Human T Leukemia Cells.
Bergermann T, Born L, Ferguson F, Latkovic P, Scheul A, Sonnenschein N, Leanza L, Keitsch S, Sehl C, Wilker B, Edwards MJ, Zoratti M, Paradisi C, Kohnen M, Szabo I, Becker KA, Carpinteiro A. Bergermann T, et al. Among authors: keitsch s. Cell Physiol Biochem. 2019;53(S1):1-10. doi: 10.33594/000000187. Cell Physiol Biochem. 2019. PMID: 31804046 Free article.
Clinical Development of Sphingosine as Anti-Bacterial Drug: Inhalation of Sphingosine in Mini Pigs has no Adverse Side Effects.
Carstens H, Schumacher F, Keitsch S, Kramer M, Kühn C, Sehl C, Soddemann M, Wilker B, Herrmann D, Swaidan A, Kleuser B, Verhaegh R, Hilken G, Edwards MJ, Dubicanac M, Carpinteiro A, Wissmann A, Becker KA, Kamler M, Gulbins E. Carstens H, et al. Among authors: keitsch s. Cell Physiol Biochem. 2019;53(6):1015-1028. doi: 10.33594/000000194. Cell Physiol Biochem. 2019. PMID: 31854953 Free article.
Sphingosine prevents binding of SARS-CoV-2 spike to its cellular receptor ACE2.
Edwards MJ, Becker KA, Gripp B, Hoffmann M, Keitsch S, Wilker B, Soddemann M, Gulbins A, Carpinteiro E, Patel SH, Wilson GC, Pöhlmann S, Walter S, Fassbender K, Ahmad SA, Carpinteiro A, Gulbins E. Edwards MJ, et al. Among authors: keitsch s. J Biol Chem. 2020 Nov 6;295(45):15174-15182. doi: 10.1074/jbc.RA120.015249. Epub 2020 Sep 11. J Biol Chem. 2020. PMID: 32917722 Free PMC article.
26 results