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The High-Resolution Structure Reveals Remarkable Similarity in PD-1 Binding of Cemiplimab and Dostarlimab, the FDA-Approved Antibodies for Cancer Immunotherapy.
Biomedicines. 2022 Dec 6;10(12):3154. doi: 10.3390/biomedicines10123154.
Biomedicines. 2022.
PMID: 36551910
Free PMC article.
Molecular basis of PD-1 blockade by dostarlimab, the FDA-approved antibody for cancer immunotherapy.
Park UB, Jeong TJ, Gu N, Lee HT, Heo YS.
Park UB, et al.
Biochem Biophys Res Commun. 2022 Apr 9;599:31-37. doi: 10.1016/j.bbrc.2022.02.026. Epub 2022 Feb 9.
Biochem Biophys Res Commun. 2022.
PMID: 35168061
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Crystal structure of PD-1 in complex with an antibody-drug tislelizumab used in tumor immune checkpoint therapy.
Lee SH, Lee HT, Lim H, Kim Y, Park UB, Heo YS.
Lee SH, et al. Among authors: park ub.
Biochem Biophys Res Commun. 2020 Jun 18;527(1):226-231. doi: 10.1016/j.bbrc.2020.04.121. Epub 2020 May 1.
Biochem Biophys Res Commun. 2020.
PMID: 32446372
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Crystal structure of CD38 in complex with daratumumab, a first-in-class anti-CD38 antibody drug for treating multiple myeloma.
Lee HT, Kim Y, Park UB, Jeong TJ, Lee SH, Heo YS.
Lee HT, et al. Among authors: park ub.
Biochem Biophys Res Commun. 2021 Jan 15;536:26-31. doi: 10.1016/j.bbrc.2020.12.048. Epub 2020 Dec 22.
Biochem Biophys Res Commun. 2021.
PMID: 33360095
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High-resolution structure of the vWF A1 domain in complex with caplacizumab, the first nanobody-based medicine for treating acquired TTP.
Lee HT, Park UB, Jeong TJ, Gu N, Lee SH, Kim Y, Heo YS.
Lee HT, et al. Among authors: park ub.
Biochem Biophys Res Commun. 2021 Aug 27;567:49-55. doi: 10.1016/j.bbrc.2021.06.030. Epub 2021 Jun 16.
Biochem Biophys Res Commun. 2021.
PMID: 34144500
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