Kühn R - Search Results

1

Branch point strength controls species-specific CAMK2B alternative splicing and regulates LTP.

Franz A, Weber AI, Preußner M, Dimos N, Stumpf A, Ji Y, Moreno-Velasquez L, Voigt A, Schulz F, Neumann A, Kuropka B, Kühn R, Urlaub H, Schmitz D, Wahl MC, Heyd F. Franz A, et al. Among authors: kuhn r. Life Sci Alliance. 2022 Dec 21;6(3):e202201826. doi: 10.26508/lsa.202201826. Print 2023 Mar. Life Sci Alliance. 2022. PMID: 36543542 Free PMC article.

2

A homology independent sequence replacement strategy in human cells using a CRISPR nuclease.

Danner E, Lebedin M, de la Rosa K, Kühn R. Danner E, et al. Among authors: kuhn r. Open Biol. 2021 Jan;11(1):200283. doi: 10.1098/rsob.200283. Epub 2021 Jan 27. Open Biol. 2021. PMID: 33499763 Free PMC article.

3

Genome engineering in rodents - status quo and perspectives.

Kühn R. Kühn R. Lab Anim. 2022 Feb;56(1):83-87. doi: 10.1177/00236772211051842. Epub 2021 Oct 21. Lab Anim. 2022. PMID: 34674587 Review.

4

Generation of a NES-mScarlet Red Fluorescent Reporter Human iPSC Line for Live Cell Imaging and Flow Cytometric Analysis and Sorting Using CRISPR-Cas9-Mediated Gene Editing.

Nouri P, Zimmer A, Brüggemann S, Friedrich R, Kühn R, Prakash N. Nouri P, et al. Among authors: kuhn r. Cells. 2022 Jan 13;11(2):268. doi: 10.3390/cells11020268. Cells. 2022. PMID: 35053384 Free PMC article.

5

Precise CRISPR-Cas-mediated gene repair with minimal off-target and unintended on-target mutations in human hematopoietic stem cells.

Tran NT, Danner E, Li X, Graf R, Lebedin M, de la Rosa K, Kühn R, Rajewsky K, Chu VT. Tran NT, et al. Among authors: kuhn r. Sci Adv. 2022 Jun 3;8(22):eabm9106. doi: 10.1126/sciadv.abm9106. Epub 2022 Jun 3. Sci Adv. 2022. PMID: 35658035 Free PMC article.

6

Efficient CRISPR/Cas9-Mediated Gene Knockin in Mouse Hematopoietic Stem and Progenitor Cells.

Tran NT, Sommermann T, Graf R, Trombke J, Pempe J, Petsch K, Kühn R, Rajewsky K, Chu VT. Tran NT, et al. Among authors: kuhn r. Cell Rep. 2019 Sep 24;28(13):3510-3522.e5. doi: 10.1016/j.celrep.2019.08.065. Cell Rep. 2019. PMID: 31553918 Free PMC article.

7

A RAS-Independent Biomarker Panel to Reliably Predict Response to MEK Inhibition in Colorectal Cancer.

Pfohl U, Loskutov J, Bashir S, Kühn R, Herter P, Templin M, Mamlouk S, Belanov S, Linnebacher M, Bürtin F, Vetter M, Reinhard C, Wedeken L, Regenbrecht CRA. Pfohl U, et al. Among authors: kuhn r. Cancers (Basel). 2022 Jul 1;14(13):3252. doi: 10.3390/cancers14133252. Cancers (Basel). 2022. PMID: 35805024 Free PMC article.

8

In vivo dissection of a clustered-CTCF domain boundary reveals developmental principles of regulatory insulation.

Anania C, Acemel RD, Jedamzick J, Bolondi A, Cova G, Brieske N, Kühn R, Wittler L, Real FM, Lupiáñez DG. Anania C, et al. Among authors: kuhn r. Nat Genet. 2022 Jul;54(7):1026-1036. doi: 10.1038/s41588-022-01117-9. Epub 2022 Jul 11. Nat Genet. 2022. PMID: 35817979 Free PMC article.

9

Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function.

Piwecka M, Glažar P, Hernandez-Miranda LR, Memczak S, Wolf SA, Rybak-Wolf A, Filipchyk A, Klironomos F, Cerda Jara CA, Fenske P, Trimbuch T, Zywitza V, Plass M, Schreyer L, Ayoub S, Kocks C, Kühn R, Rosenmund C, Birchmeier C, Rajewsky N. Piwecka M, et al. Among authors: kuhn r. Science. 2017 Sep 22;357(6357):eaam8526. doi: 10.1126/science.aam8526. Epub 2017 Aug 10. Science. 2017. PMID: 28798046

10

Pop in, pop out: a novel gene-targeting strategy for use with CRISPR-Cas9.

Kühn R, Chu VT. Kühn R, et al. Genome Biol. 2015 Nov 10;16:244. doi: 10.1186/s13059-015-0810-2. Genome Biol. 2015. PMID: 26553112 Free PMC article.

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