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Abacavir causes leukocyte/platelet crosstalk by activating neutrophil P2X7 receptors thus releasing soluble lectin-like oxidized low-density lipoprotein receptor-1.
Br J Pharmacol. 2023 Jun;180(11):1516-1532. doi: 10.1111/bph.16016. Epub 2023 Jan 18.
Br J Pharmacol. 2023.
PMID: 36541109
Role of Neutrophil Extracellular Traps in COVID-19 Progression: An Insight for Effective Treatment.
Blanch-Ruiz MA, Ortega-Luna R, Gómez-García G, Martínez-Cuesta MÁ, Álvarez Á.
Blanch-Ruiz MA, et al.
Biomedicines. 2021 Dec 23;10(1):31. doi: 10.3390/biomedicines10010031.
Biomedicines. 2021.
PMID: 35052711
Free PMC article.
Review.
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The Neutrophil Secretome as a Crucial Link between Inflammation and Thrombosis.
Blanch-Ruiz MA, Ortega-Luna R, Martínez-Cuesta MÁ, Álvarez Á.
Blanch-Ruiz MA, et al.
Int J Mol Sci. 2021 Apr 17;22(8):4170. doi: 10.3390/ijms22084170.
Int J Mol Sci. 2021.
PMID: 33920656
Free PMC article.
Review.
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Abacavir Increases Purinergic P2X7 Receptor Activation by ATP: Does a Pro-inflammatory Synergism Underlie Its Cardiovascular Toxicity?
Collado-Díaz V, Martinez-Cuesta MÁ, Blanch-Ruiz MA, Sánchez-López A, García-Martínez P, Peris JE, Usach I, Ivorra MD, Lacetera A, Martín-Santamaría S, Esplugues JV, Alvarez A.
Collado-Díaz V, et al. Among authors: blanch ruiz ma.
Front Pharmacol. 2021 Mar 31;12:613449. doi: 10.3389/fphar.2021.613449. eCollection 2021.
Front Pharmacol. 2021.
PMID: 33867979
Free PMC article.
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Structural and Functional Basis for Understanding the Biological Significance of P2X7 Receptor.
Martínez-Cuesta MÁ, Blanch-Ruiz MA, Ortega-Luna R, Sánchez-López A, Álvarez Á.
Martínez-Cuesta MÁ, et al. Among authors: blanch ruiz ma.
Int J Mol Sci. 2020 Nov 10;21(22):8454. doi: 10.3390/ijms21228454.
Int J Mol Sci. 2020.
PMID: 33182829
Free PMC article.
Review.
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Abacavir Induces Arterial Thrombosis in a Murine Model.
Collado-Diaz V, Andujar I, Sanchez-Lopez A, Orden S, Blanch-Ruiz MA, Martinez-Cuesta MA, Blas-García A, Esplugues JV, Álvarez Á.
Collado-Diaz V, et al. Among authors: blanch ruiz ma.
J Infect Dis. 2018 Jun 20;218(2):228-233. doi: 10.1093/infdis/jiy001.
J Infect Dis. 2018.
PMID: 29346575
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Abacavir induces platelet-endothelium interactions by interfering with purinergic signalling: A step from inflammation to thrombosis.
Alvarez A, Rios-Navarro C, Blanch-Ruiz MA, Collado-Diaz V, Andujar I, Martinez-Cuesta MA, Orden S, Esplugues JV.
Alvarez A, et al. Among authors: blanch ruiz ma.
Antiviral Res. 2017 May;141:179-185. doi: 10.1016/j.antiviral.2017.03.001. Epub 2017 Mar 2.
Antiviral Res. 2017.
PMID: 28263802
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