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Miz1 promotes KRAS-driven lung tumorigenesis by repressing the protocadherin Pcdh10.
Yang J, Hou C, Wang H, Perez EA, Do-Umehara HC, Dong H, Arunagiri V, Tong F, Van Scoyk M, Cho M, Liu X, Ge X, Winn RA, Ridge KM, Wang X, Chandel NS, Liu J. Yang J, et al. Among authors: do umehara hc. Cancer Lett. 2023 Feb 28;555:216025. doi: 10.1016/j.canlet.2022.216025. Epub 2022 Dec 17. Cancer Lett. 2023. PMID: 36538983 Free PMC article.
Cilia-related gene signature in the nasal mucosa correlates with disease severity and outcomes in critical respiratory syncytial virus bronchiolitis.
Koch CM, Prigge AD, Setar L, Anekalla KR, Do-Umehara HC, Abdala-Valencia H, Politanska Y, Shukla A, Chavez J, Hahn GR, Coates BM. Koch CM, et al. Among authors: do umehara hc. Front Immunol. 2022 Sep 23;13:924792. doi: 10.3389/fimmu.2022.924792. eCollection 2022. Front Immunol. 2022. PMID: 36211387 Free PMC article.
miR-221-5p-Mediated Downregulation of JNK2 Aggravates Acute Lung Injury.
Yang J, Do-Umehara HC, Zhang Q, Wang H, Hou C, Dong H, Perez EA, Sala MA, Anekalla KR, Walter JM, Liu S, Wunderink RG, Budinger GRS, Liu J. Yang J, et al. Among authors: do umehara hc. Front Immunol. 2021 Nov 25;12:700933. doi: 10.3389/fimmu.2021.700933. eCollection 2021. Front Immunol. 2021. PMID: 34899681 Free PMC article.
Age-related Differences in the Nasal Mucosal Immune Response to SARS-CoV-2.
Koch CM, Prigge AD, Anekalla KR, Shukla A, Do Umehara HC, Setar L, Chavez J, Abdala-Valencia H, Politanska Y, Markov NS, Hahn GR, Heald-Sargent T, Sanchez-Pinto LN, Muller WJ, Singer BD, Misharin AV, Ridge KM, Coates BM. Koch CM, et al. Among authors: do umehara hc. Am J Respir Cell Mol Biol. 2022 Feb;66(2):206-222. doi: 10.1165/rcmb.2021-0292OC. Am J Respir Cell Mol Biol. 2022. PMID: 34731594 Free PMC article.
Immune response to SARS-CoV-2 in the nasal mucosa in children and adults.
Koch CM, Prigge AD, Anekalla KR, Shukla A, Do-Umehara HC, Setar L, Chavez J, Abdala-Valencia H, Politanska Y, Markov NS, Hahn GR, Heald-Sargent T, Sanchez-Pinto LN, Muller WJ, Misharin AV, Ridge KM, Coates BM. Koch CM, et al. Among authors: do umehara hc. medRxiv [Preprint]. 2021 Jan 28:2021.01.26.21250269. doi: 10.1101/2021.01.26.21250269. medRxiv. 2021. PMID: 33532801 Free PMC article. Updated. Preprint.
Epithelial cell-specific loss of function of Miz1 causes a spontaneous COPD-like phenotype and up-regulates Ace2 expression in mice.
Do-Umehara HC, Chen C, Zhang Q, Misharin AV, Abdala-Valencia H, Casalino-Matsuda SM, Reyfman PA, Anekalla KR, Gonzalez-Gonzalez FJ, Sala MA, Peng C, Wu P, Wong CCL, Kalhan R, Bharat A, Perlman H, Ridge KM, Sznajder JI, Sporn PHS, Chandel NS, Yu J, Fu X, Petrache I, Tuder R, Budinger GRS, Liu J. Do-Umehara HC, et al. Sci Adv. 2020 Aug 14;6(33):eabb7238. doi: 10.1126/sciadv.abb7238. eCollection 2020 Aug. Sci Adv. 2020. PMID: 32851183 Free PMC article.
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