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Some recent developments in the preparation of novel recognition systems: a recognition site for the selective catalysis of an aldol condensation using molecular imprinting and specific affinity motifs for alpha-chymotrypsin using a phage display peptide library.
Nicholls IA, Matsui J, Krook M, Mosbach K. Nicholls IA, et al. J Mol Recognit. 1996 Sep-Dec;9(5-6):652-7. doi: 10.1002/(sici)1099-1352(199634/12)9:5/6<652::aid-jmr316>3.0.co;2-6. J Mol Recognit. 1996. PMID: 9174952
Safety and efficacy of the cystic fibrosis transmembrane conductance regulator potentiator icenticaftor (QBW251).
Kazani S, Rowlands DJ, Bottoli I, Milojevic J, Alcantara J, Jones I, Kulmatycki K, Machineni S, Mostovy L, Nicholls I, Nick JA, Rowe SM, Simmonds NJ, Vegesna R, Verheijen J, Danahay H, Gosling M, Ayalavajjala PS, Salman M, Strieter R. Kazani S, et al. J Cyst Fibros. 2021 Mar;20(2):250-256. doi: 10.1016/j.jcf.2020.11.002. Epub 2020 Dec 6. J Cyst Fibros. 2021. PMID: 33293212 Free PMC article.
An artificial estrogen receptor through combinatorial imprinting.
Schillinger E, Möder M, Olsson GD, Nicholls IA, Sellergren B. Schillinger E, et al. Among authors: nicholls ia. Chemistry. 2012 Nov 12;18(46):14773-83. doi: 10.1002/chem.201201428. Epub 2012 Sep 27. Chemistry. 2012. PMID: 23018616
Discovery of Icenticaftor (QBW251), a Cystic Fibrosis Transmembrane Conductance Regulator Potentiator with Clinical Efficacy in Cystic Fibrosis and Chronic Obstructive Pulmonary Disease.
Grand DL, Gosling M, Baettig U, Bahra P, Bala K, Brocklehurst C, Budd E, Butler R, Cheung AK, Choudhury H, Collingwood SP, Cox B, Danahay H, Edwards L, Everatt B, Glaenzel U, Glotin AL, Groot-Kormelink P, Hall E, Hatto J, Howsham C, Hughes G, King A, Koehler J, Kulkarni S, Lightfoot M, Nicholls I, Page C, Pergl-Wilson G, Popa MO, Robinson R, Rowlands D, Sharp T, Spendiff M, Stanley E, Steward O, Taylor RJ, Tranter P, Wagner T, Watson H, Williams G, Wright P, Young A, Sandham DA. Grand DL, et al. J Med Chem. 2021 Jun 10;64(11):7241-7260. doi: 10.1021/acs.jmedchem.1c00343. Epub 2021 May 24. J Med Chem. 2021. PMID: 34028270
Actomyosin motility on nanostructured surfaces.
Bunk R, Klinth J, Montelius L, Nicholls IA, Omling P, Tågerud S, Månsson A. Bunk R, et al. Among authors: nicholls ia. Biochem Biophys Res Commun. 2003 Feb 14;301(3):783-8. doi: 10.1016/s0006-291x(03)00027-5. Biochem Biophys Res Commun. 2003. PMID: 12565849
105 results