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Acylated 1H-1,2,4-Triazol-5-amines Targeting Human Coagulation Factor XIIa and Thrombin: Conventional and Microscale Synthesis, Anticoagulant Properties, and Mechanism of Action.
Korff M, Imberg L, Will JM, Bückreiß N, Kalinina SA, Wenzel BM, Kastner GA, Daniliuc CG, Barth M, Ovsepyan RA, Butov KR, Humpf HU, Lehr M, Panteleev MA, Poso A, Karst U, Steinmetzer T, Bendas G, Kalinin DV. Korff M, et al. Among authors: poso a. J Med Chem. 2020 Nov 12;63(21):13159-13186. doi: 10.1021/acs.jmedchem.0c01635. Epub 2020 Oct 22. J Med Chem. 2020. PMID: 33089691
Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity.
Flury P, Breidenbach J, Krüger N, Voget R, Schäkel L, Si Y, Krasniqi V, Calistri S, Olfert M, Sylvester K, Rocha C, Ditzinger R, Rasch A, Pöhlmann S, Kronenberger T, Poso A, Rox K, Laufer SA, Müller CE, Gütschow M, Pillaiyar T. Flury P, et al. Among authors: poso a. ACS Pharmacol Transl Sci. 2024 Jan 19;7(2):493-514. doi: 10.1021/acsptsci.3c00313. eCollection 2024 Feb 9. ACS Pharmacol Transl Sci. 2024. PMID: 38357286
Correction to "Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity".
Flury P, Breidenbach J, Krüger N, Voget R, Schäkel L, Si Y, Krasniqi V, Calistri S, Olfert M, Sylvester K, Rocha C, Ditzinger R, Rasch A, Pöhlmann S, Kronenberger T, Poso A, Rox K, Laufer SA, Müller CE, Gütschow M, Pillaiyar T. Flury P, et al. Among authors: poso a. ACS Pharmacol Transl Sci. 2024 Mar 6;7(4):1195-1196. doi: 10.1021/acsptsci.4c00095. eCollection 2024 Apr 12. ACS Pharmacol Transl Sci. 2024. PMID: 38633592 Free article.
Peptides and Pseudopeptides as SIRT6 Deacetylation Inhibitors.
Kokkonen P, Rahnasto-Rilla M, Kiviranta PH, Huhtiniemi T, Laitinen T, Poso A, Jarho E, Lahtela-Kakkonen M. Kokkonen P, et al. Among authors: poso a. ACS Med Chem Lett. 2012 Oct 23;3(12):969-74. doi: 10.1021/ml300139n. eCollection 2012 Dec 13. ACS Med Chem Lett. 2012. PMID: 24900419 Free PMC article.
Potent Inhibitor of Human Trypsins from the Aeruginosin Family of Natural Products.
Ahmed MN, Wahlsten M, Jokela J, Nees M, Stenman UH, Alvarenga DO, Strandin T, Sivonen K, Poso A, Permi P, Metsä-Ketelä M, Koistinen H, Fewer DP. Ahmed MN, et al. Among authors: poso a. ACS Chem Biol. 2021 Nov 19;16(11):2537-2546. doi: 10.1021/acschembio.1c00611. Epub 2021 Oct 18. ACS Chem Biol. 2021. PMID: 34661384 Free PMC article.
1,3,4-Oxadiazol-2-ones as fatty-acid amide hydrolase and monoacylglycerol lipase inhibitors: Synthesis, in vitro evaluation and insight into potency and selectivity determinants by molecular modelling.
Käsnänen H, Minkkilä A, Taupila S, Patel JZ, Parkkari T, Lahtela-Kakkonen M, Saario SM, Nevalainen T, Poso A. Käsnänen H, et al. Among authors: poso a. Eur J Pharm Sci. 2013 Jun 14;49(3):423-33. doi: 10.1016/j.ejps.2013.03.015. Epub 2013 Apr 2. Eur J Pharm Sci. 2013. PMID: 23557840
297 results