Prodromou C - Search Results

1

HSP70-HSP90 Chaperone Networking in Protein-Misfolding Disease.

Prodromou C, Aran-Guiu X, Oberoi J, Perna L, Chapple JP, van der Spuy J. Prodromou C, et al. Subcell Biochem. 2023;101:389-425. doi: 10.1007/978-3-031-14740-1_13. Subcell Biochem. 2023. PMID: 36520314 Review.

2

DNA fragmentation-based combinatorial approaches to soluble protein expression Part I. Generating DNA fragment libraries.

Prodromou C, Savva R, Driscoll PC. Prodromou C, et al. Drug Discov Today. 2007 Nov;12(21-22):931-8. doi: 10.1016/j.drudis.2007.08.012. Epub 2007 Oct 23. Drug Discov Today. 2007. PMID: 17993411 Review.

3

Combinatorial Domain Hunting: An effective approach for the identification of soluble protein domains adaptable to high-throughput applications.

Reich S, Puckey LH, Cheetham CL, Harris R, Ali AA, Bhattacharyya U, Maclagan K, Powell KA, Prodromou C, Pearl LH, Driscoll PC, Savva R. Reich S, et al. Among authors: prodromou c. Protein Sci. 2006 Oct;15(10):2356-65. doi: 10.1110/ps.062082606. Protein Sci. 2006. PMID: 17008718 Free PMC article.

4

DNA fragmentation based combinatorial approaches to soluble protein expression Part II: library expression, screening and scale-up.

Savva R, Prodromou C, Driscoll PC. Savva R, et al. Among authors: prodromou c. Drug Discov Today. 2007 Nov;12(21-22):939-47. doi: 10.1016/j.drudis.2007.08.016. Epub 2007 Oct 22. Drug Discov Today. 2007. PMID: 17993412

5

Regulation of Hsp90 ATPase activity by the co-chaperone Cdc37p/p50cdc37.

Siligardi G, Panaretou B, Meyer P, Singh S, Woolfson DN, Piper PW, Pearl LH, Prodromou C. Siligardi G, et al. Among authors: prodromou c. J Biol Chem. 2002 Jun 7;277(23):20151-9. doi: 10.1074/jbc.M201287200. Epub 2002 Mar 26. J Biol Chem. 2002. PMID: 11916974 Free article.

6

Sensitivity to Hsp90-targeting drugs can arise with mutation to the Hsp90 chaperone, cochaperones and plasma membrane ATP binding cassette transporters of yeast.

Piper PW, Millson SH, Mollapour M, Panaretou B, Siligardi G, Pearl LH, Prodromou C. Piper PW, et al. Among authors: prodromou c. Eur J Biochem. 2003 Dec;270(23):4689-95. doi: 10.1046/j.1432-1033.2003.03866.x. Eur J Biochem. 2003. PMID: 14622256 Free article.

7

Structure and mechanism of the Hsp90 molecular chaperone machinery.

Pearl LH, Prodromou C. Pearl LH, et al. Among authors: prodromou c. Annu Rev Biochem. 2006;75:271-94. doi: 10.1146/annurev.biochem.75.103004.142738. Annu Rev Biochem. 2006. PMID: 16756493 Review.

8

The 'active life' of Hsp90 complexes.

Prodromou C. Prodromou C. Biochim Biophys Acta. 2012 Mar;1823(3):614-23. doi: 10.1016/j.bbamcr.2011.07.020. Epub 2011 Aug 4. Biochim Biophys Acta. 2012. PMID: 21840346 Free PMC article. Review.

9

ATP-competitive inhibitors block protein kinase recruitment to the Hsp90-Cdc37 system.

Polier S, Samant RS, Clarke PA, Workman P, Prodromou C, Pearl LH. Polier S, et al. Among authors: prodromou c. Nat Chem Biol. 2013 May;9(5):307-12. doi: 10.1038/nchembio.1212. Epub 2013 Mar 17. Nat Chem Biol. 2013. PMID: 23502424 Free PMC article.

10

Asymmetric Hsp90 N domain SUMOylation recruits Aha1 and ATP-competitive inhibitors.

Mollapour M, Bourboulia D, Beebe K, Woodford MR, Polier S, Hoang A, Chelluri R, Li Y, Guo A, Lee MJ, Fotooh-Abadi E, Khan S, Prince T, Miyajima N, Yoshida S, Tsutsumi S, Xu W, Panaretou B, Stetler-Stevenson WG, Bratslavsky G, Trepel JB, Prodromou C, Neckers L. Mollapour M, et al. Among authors: prodromou c. Mol Cell. 2014 Jan 23;53(2):317-29. doi: 10.1016/j.molcel.2013.12.007. Mol Cell. 2014. PMID: 24462205 Free PMC article.

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