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The suppressor of copper sensitivity protein C from Caulobacter crescentus is a trimeric disulfide isomerase that binds copper(I) with subpicomolar affinity.
Petit GA, Hong Y, Djoko KY, Whitten AE, Furlong EJ, McCoy AJ, Gulbis JM, Totsika M, Martin JL, Halili MA. Petit GA, et al. Among authors: gulbis jm. Acta Crystallogr D Struct Biol. 2022 Mar 1;78(Pt 3):337-352. doi: 10.1107/S2059798322000729. Epub 2022 Feb 21. Acta Crystallogr D Struct Biol. 2022. PMID: 35234148 Free PMC article.
Ion currents through Kir potassium channels are gated by anionic lipids.
Jin R, He S, Black KA, Clarke OB, Wu D, Bolla JR, Johnson P, Periasamy A, Wardak A, Czabotar P, Colman PM, Robinson CV, Laver D, Smith BJ, Gulbis JM. Jin R, et al. Among authors: gulbis jm. Nat Commun. 2022 Jan 25;13(1):490. doi: 10.1038/s41467-022-28148-4. Nat Commun. 2022. PMID: 35079013 Free PMC article.
BAK core dimers bind lipids and can be bridged by them.
Cowan AD, Smith NA, Sandow JJ, Kapp EA, Rustam YH, Murphy JM, Brouwer JM, Bernardini JP, Roy MJ, Wardak AZ, Tan IK, Webb AI, Gulbis JM, Smith BJ, Reid GE, Dewson G, Colman PM, Czabotar PE. Cowan AD, et al. Among authors: gulbis jm. Nat Struct Mol Biol. 2020 Nov;27(11):1024-1031. doi: 10.1038/s41594-020-0494-5. Epub 2020 Sep 14. Nat Struct Mol Biol. 2020. PMID: 32929280
A constricted opening in Kir channels does not impede potassium conduction.
Black KA, He S, Jin R, Miller DM, Bolla JR, Clarke OB, Johnson P, Windley M, Burns CJ, Hill AP, Laver D, Robinson CV, Smith BJ, Gulbis JM. Black KA, et al. Among authors: gulbis jm. Nat Commun. 2020 Jun 15;11(1):3024. doi: 10.1038/s41467-020-16842-0. Nat Commun. 2020. PMID: 32541684 Free PMC article.
Editorial overview: Membranes.
Gulbis JM, Waksman G. Gulbis JM, et al. Curr Opin Struct Biol. 2016 Aug;39:vii-ix. doi: 10.1016/j.sbi.2016.09.004. Epub 2016 Sep 17. Curr Opin Struct Biol. 2016. PMID: 27646477 No abstract available.
32 results