Schaks M - Search Results

1

Arf GTPase activates the WAVE regulatory complex through a distinct binding site.

Yang S, Tang Y, Liu Y, Brown AJ, Schaks M, Ding B, Kramer DA, Mietkowska M, Ding L, Alekhina O, Billadeau DD, Chowdhury S, Wang J, Rottner K, Chen B. Yang S, et al. Among authors: schaks m. Sci Adv. 2022 Dec 14;8(50):eadd1412. doi: 10.1126/sciadv.add1412. Epub 2022 Dec 14. Sci Adv. 2022. PMID: 36516255 Free PMC article.

2

Reduced expression and activity of patient-derived SHIP1 phosphatase domain mutants.

Ehm P, Nelson N, Giehler S, Schaks M, Bettin B, Kirchmair J, Jücker M. Ehm P, et al. Among authors: schaks m. Cell Signal. 2023 Jan;101:110485. doi: 10.1016/j.cellsig.2022.110485. Epub 2022 Oct 5. Cell Signal. 2023. PMID: 36208705

3

Structures reveal a key mechanism of WAVE regulatory complex activation by Rac1 GTPase.

Ding B, Yang S, Schaks M, Liu Y, Brown AJ, Rottner K, Chowdhury S, Chen B. Ding B, et al. Among authors: schaks m. Nat Commun. 2022 Sep 16;13(1):5444. doi: 10.1038/s41467-022-33174-3. Nat Commun. 2022. PMID: 36114192 Free PMC article.

4

Lamellipodia-like actin networks in cells lacking WAVE regulatory complex.

Kage F, Döring H, Mietkowska M, Schaks M, Grüner F, Stahnke S, Steffen A, Müsken M, Stradal TEB, Rottner K. Kage F, et al. Among authors: schaks m. J Cell Sci. 2022 Aug 1;135(15):jcs260364. doi: 10.1242/jcs.260364. Epub 2022 Aug 16. J Cell Sci. 2022. PMID: 35971979 Free PMC article.

5

Forces generated by lamellipodial actin filament elongation regulate the WAVE complex during cell migration.

Mehidi A, Kage F, Karatas Z, Cercy M, Schaks M, Polesskaya A, Sainlos M, Gautreau AM, Rossier O, Rottner K, Giannone G. Mehidi A, et al. Among authors: schaks m. Nat Cell Biol. 2021 Nov;23(11):1148-1162. doi: 10.1038/s41556-021-00786-8. Epub 2021 Nov 4. Nat Cell Biol. 2021. PMID: 34737443

6

A barbed end interference mechanism reveals how capping protein promotes nucleation in branched actin networks.

Funk J, Merino F, Schaks M, Rottner K, Raunser S, Bieling P. Funk J, et al. Among authors: schaks m. Nat Commun. 2021 Sep 9;12(1):5329. doi: 10.1038/s41467-021-25682-5. Nat Commun. 2021. PMID: 34504078 Free PMC article.

7

Cell-substrate adhesion drives Scar/WAVE activation and phosphorylation by a Ste20-family kinase, which controls pseudopod lifetime.

Singh SP, Thomason PA, Lilla S, Schaks M, Tang Q, Goode BL, Machesky LM, Rottner K, Insall RH. Singh SP, et al. Among authors: schaks m. PLoS Biol. 2020 Aug 3;18(8):e3000774. doi: 10.1371/journal.pbio.3000774. eCollection 2020 Aug. PLoS Biol. 2020. PMID: 32745097 Free PMC article.

8

WAVE1 and WAVE2 have distinct and overlapping roles in controlling actin assembly at the leading edge.

Tang Q, Schaks M, Koundinya N, Yang C, Pollard LW, Svitkina TM, Rottner K, Goode BL. Tang Q, et al. Among authors: schaks m. Mol Biol Cell. 2020 Sep 15;31(20):2168-2178. doi: 10.1091/mbc.E19-12-0705. Epub 2020 Jul 22. Mol Biol Cell. 2020. PMID: 32697617 Free PMC article.

9

Ectopic Expression of Hematopoietic SHIP1 in Human Colorectal Cancer.

Schaks M, Allgoewer K, Nelson N, Ehm P, Heumann A, Ewald F, Schumacher U, Simon R, Sauter G, Jücker M. Schaks M, et al. Biomedicines. 2020 Jul 15;8(7):215. doi: 10.3390/biomedicines8070215. Biomedicines. 2020. PMID: 32679836 Free PMC article.

10

Molecular Dissection of Neurodevelopmental Disorder-Causing Mutations in CYFIP2.

Schaks M, Reinke M, Witke W, Rottner K. Schaks M, et al. Cells. 2020 May 29;9(6):1355. doi: 10.3390/cells9061355. Cells. 2020. PMID: 32486060 Free PMC article.

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