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A remarkable adaptive paradigm of heart performance and protection emerges in response to marked cardiac-specific overexpression of ADCY8.
Tarasov KV, Chakir K, Riordon DR, Lyashkov AE, Ahmet I, Perino MG, Silvester AJ, Zhang J, Wang M, Lukyanenko YO, Qu JH, Barrera MC, Juhaszova M, Tarasova YS, Ziman B, Telljohann R, Kumar V, Ranek M, Lammons J, Bychkov R, de Cabo R, Jun S, Keceli G, Gupta A, Yang D, Aon MA, Adamo L, Morrell CH, Otu W, Carroll C, Chambers S, Paolocci N, Huynh T, Pacak K, Weiss R, Field L, Sollott SJ, Lakatta EG. Tarasov KV, et al. Among authors: yang d. Elife. 2022 Dec 14;11:e80949. doi: 10.7554/eLife.80949. Elife. 2022. PMID: 36515265 Free PMC article.
Phosphoprotein Phosphatase 1 but Not 2A Activity Modulates Coupled-Clock Mechanisms to Impact on Intrinsic Automaticity of Sinoatrial Nodal Pacemaker Cells.
Sirenko ST, Zahanich I, Li Y, Lukyanenko YO, Lyashkov AE, Ziman BD, Tarasov KV, Younes A, Riordon DR, Tarasova YS, Yang D, Vinogradova TM, Maltsev VA, Lakatta EG. Sirenko ST, et al. Among authors: yang d. Cells. 2021 Nov 10;10(11):3106. doi: 10.3390/cells10113106. Cells. 2021. PMID: 34831329 Free PMC article.
Real-time relationship between PKA biochemical signal network dynamics and increased action potential firing rate in heart pacemaker cells: Kinetics of PKA activation in heart pacemaker cells.
Yaniv Y, Ganesan A, Yang D, Ziman BD, Lyashkov AE, Levchenko A, Zhang J, Lakatta EG. Yaniv Y, et al. Among authors: yang d. J Mol Cell Cardiol. 2015 Sep;86:168-78. doi: 10.1016/j.yjmcc.2015.07.024. Epub 2015 Aug 1. J Mol Cell Cardiol. 2015. PMID: 26241846 Free PMC article.
Self-Similar Synchronization of Calcium and Membrane Potential Transitions During Action Potential Cycles Predict Heart Rate Across Species.
Tagirova Sirenko S, Tsutsui K, Tarasov KV, Yang D, Wirth AN, Maltsev VA, Ziman BD, Yaniv Y, Lakatta EG. Tagirova Sirenko S, et al. Among authors: yang d. JACC Clin Electrophysiol. 2021 Nov;7(11):1331-1344. doi: 10.1016/j.jacep.2021.02.016. Epub 2021 Apr 28. JACC Clin Electrophysiol. 2021. PMID: 33933406 Free PMC article.
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