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A remarkable adaptive paradigm of heart performance and protection emerges in response to marked cardiac-specific overexpression of ADCY8.
Tarasov KV, Chakir K, Riordon DR, Lyashkov AE, Ahmet I, Perino MG, Silvester AJ, Zhang J, Wang M, Lukyanenko YO, Qu JH, Barrera MC, Juhaszova M, Tarasova YS, Ziman B, Telljohann R, Kumar V, Ranek M, Lammons J, Bychkov R, de Cabo R, Jun S, Keceli G, Gupta A, Yang D, Aon MA, Adamo L, Morrell CH, Otu W, Carroll C, Chambers S, Paolocci N, Huynh T, Pacak K, Weiss R, Field L, Sollott SJ, Lakatta EG. Tarasov KV, et al. Among authors: gupta a. Elife. 2022 Dec 14;11:e80949. doi: 10.7554/eLife.80949. Elife. 2022. PMID: 36515265 Free PMC article.
Mitochondrial Creatine Kinase Attenuates Pathologic Remodeling in Heart Failure.
Keceli G, Gupta A, Sourdon J, Gabr R, Schär M, Dey S, Tocchetti CG, Stuber A, Agrimi J, Zhang Y, Leppo M, Steenbergen C, Lai S, Yanek LR, O'Rourke B, Gerstenblith G, Bottomley PA, Wang Y, Paolocci N, Weiss RG. Keceli G, et al. Among authors: gupta a. Circ Res. 2022 Mar 4;130(5):741-759. doi: 10.1161/CIRCRESAHA.121.319648. Epub 2022 Feb 3. Circ Res. 2022. PMID: 35109669 Free PMC article.
Impaired ATP kinetics in failing in vivo mouse heart.
Gupta A, Chacko VP, Schär M, Akki A, Weiss RG. Gupta A, et al. Circ Cardiovasc Imaging. 2011 Jan;4(1):42-50. doi: 10.1161/CIRCIMAGING.110.959320. Epub 2010 Oct 6. Circ Cardiovasc Imaging. 2011. PMID: 20926788 Free PMC article.
Skeletal muscle ATP kinetics are impaired in frail mice.
Akki A, Yang H, Gupta A, Chacko VP, Yano T, Leppo MK, Steenbergen C, Walston J, Weiss RG. Akki A, et al. Among authors: gupta a. Age (Dordr). 2014 Feb;36(1):21-30. doi: 10.1007/s11357-013-9540-0. Epub 2013 May 22. Age (Dordr). 2014. PMID: 23695949 Free PMC article.
Mitochondrial CaMKII causes adverse metabolic reprogramming and dilated cardiomyopathy.
Luczak ED, Wu Y, Granger JM, Joiner MA, Wilson NR, Gupta A, Umapathi P, Murphy KR, Reyes Gaido OE, Sabet A, Corradini E, Tseng WW, Wang Y, Heck AJR, Wei AC, Weiss RG, Anderson ME. Luczak ED, et al. Among authors: gupta a. Nat Commun. 2020 Sep 4;11(1):4416. doi: 10.1038/s41467-020-18165-6. Nat Commun. 2020. PMID: 32887881 Free PMC article.
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