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Mode of action of p-quinone derivatives with trypanocidal activity studied by experimental and in silico models.
Ballesteros-Casallas A, Quiroga C, Ortiz C, Benítez D, Denis PA, Figueroa D, Salas CO, Bertrand J, Tapia RA, Sánchez P, Miscione GP, Comini MA, Paulino M. Ballesteros-Casallas A, et al. Among authors: bertrand j. Eur J Med Chem. 2023 Jan 15;246:114926. doi: 10.1016/j.ejmech.2022.114926. Epub 2022 Nov 17. Eur J Med Chem. 2023. PMID: 36508970
Design, Synthesis, In Silico Studies and Inhibitory Activity towards Bcr-Abl, BTK and FLT3-ITD of New 2,6,9-Trisubstituted Purine Derivatives as Potential Agents for the Treatment of Leukaemia.
Bertrand J, Dostálová H, Kryštof V, Jorda R, Delgado T, Castro-Alvarez A, Mella J, Cabezas D, Faúndez M, Espinosa-Bustos C, Salas CO. Bertrand J, et al. Pharmaceutics. 2022 Jun 17;14(6):1294. doi: 10.3390/pharmaceutics14061294. Pharmaceutics. 2022. PMID: 35745866 Free PMC article.
New Inhibitors of Bcr-Abl Based on 2,6,9-Trisubstituted Purine Scaffold Elicit Cytotoxicity in Chronic Myeloid Leukemia-Derived Cell Lines Sensitive and Resistant to TKIs.
Delgado T, Veselá D, Dostálová H, Kryštof V, Vojáčková V, Jorda R, Castro A, Bertrand J, Rivera G, Faúndez M, Strnad M, Espinosa-Bustos C, Salas CO. Delgado T, et al. Among authors: bertrand j. Pharmaceutics. 2024 May 11;16(5):649. doi: 10.3390/pharmaceutics16050649. Pharmaceutics. 2024. PMID: 38794311 Free PMC article.
1,734 results