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A concept of dual-responsive prodrugs based on oligomerization-controlled reactivity of ester groups: an improvement of cancer cells versus neutrophils selectivity of camptothecin.
Klemt I, Reshetnikov V, Dutta S, Bila G, Bilyy R, Cuartero IC, Hidalgo A, Wünsche A, Böhm M, Wondrak M, Kunz-Schughart LA, Tietze R, Beierlein F, Imhof P, Gensberger-Reigl S, Pischetsrieder M, Körber M, Jost T, Mokhir A. Klemt I, et al. Among authors: jost t. RSC Med Chem. 2024 Jan 31;15(4):1189-1197. doi: 10.1039/d3md00609c. eCollection 2024 Apr 24. RSC Med Chem. 2024. PMID: 38665843 Free PMC article.
Radiotherapy combined with docetaxel alters the immune phenotype of HNSCC cells and results in increased surface expression of CD137 and release of HMGB1 of specifically HPV-positive tumor cells.
Grottker F, Gehre S, Reichardt CM, Sengedorj A, Jost T, Rieckmann T, Hecht M, Gostian AO, Frey B, Fietkau R, Gaipl US, Rückert M. Grottker F, et al. Among authors: jost t. Neoplasia. 2023 Nov;45:100944. doi: 10.1016/j.neo.2023.100944. Epub 2023 Oct 17. Neoplasia. 2023. PMID: 37857049 Free PMC article.
Fisetin induces DNA double-strand break and interferes with the repair of radiation-induced damage to radiosensitize triple negative breast cancer cells.
Khozooei S, Lettau K, Barletta F, Jost T, Rebholz S, Veerappan S, Franz-Wachtel M, Macek B, Iliakis G, Distel LV, Zips D, Toulany M. Khozooei S, et al. Among authors: jost t. J Exp Clin Cancer Res. 2022 Aug 22;41(1):256. doi: 10.1186/s13046-022-02442-x. J Exp Clin Cancer Res. 2022. PMID: 35989353 Free PMC article.
153 results