Smith S - Search Results

1

A Novel Model Using AAV9-Cre to Knockout Adult Leydig Cell Gene Expression Reveals a Physiological Role of Glucocorticoid Receptor Signalling in Leydig Cell Function.

Gannon AL, Darbey AL, Chensee G, Lawrence BM, O'Donnell L, Kelso J, Reed N, Parameswaran S, Smith S, Smith LB, Rebourcet D. Gannon AL, et al. Among authors: smith s, smith lb. Int J Mol Sci. 2022 Nov 30;23(23):15015. doi: 10.3390/ijms232315015. Int J Mol Sci. 2022. PMID: 36499341 Free PMC article.

2

Ablation of glucocorticoid receptor in the hindbrain of the mouse provides a novel model to investigate stress disorders.

Gannon AL, O'Hara L, Mason JI, Rebourcet D, Smith S, Traveres A, Alcaide-Corral CJ, Frederiksen H, Jørgensen A, Milne L, Mitchell RT, Smith LB. Gannon AL, et al. Among authors: smith s, smith lb. Sci Rep. 2019 Mar 1;9(1):3250. doi: 10.1038/s41598-019-39867-y. Sci Rep. 2019. PMID: 30824750 Free PMC article.

3

Low-dose tamoxifen treatment in juvenile males has long-term adverse effects on the reproductive system: implications for inducible transgenics.

Patel SH, O'Hara L, Atanassova N, Smith SE, Curley MK, Rebourcet D, Darbey AL, Gannon AL, Sharpe RM, Smith LB. Patel SH, et al. Sci Rep. 2017 Aug 21;7(1):8991. doi: 10.1038/s41598-017-09016-4. Sci Rep. 2017. PMID: 28827578 Free PMC article.

4

Leukemia Inhibitory Factor-Receptor is Dispensable for Prenatal Testis Development but is Required in Sertoli cells for Normal Spermatogenesis in Mice.

Curley M, Milne L, Smith S, Atanassova N, Rebourcet D, Darbey A, Hadoke PWF, Wells S, Smith LB. Curley M, et al. Among authors: smith s, smith lb. Sci Rep. 2018 Aug 1;8(1):11532. doi: 10.1038/s41598-018-30011-w. Sci Rep. 2018. PMID: 30068994 Free PMC article.

5

A young testicular microenvironment protects Leydig cells against age-related dysfunction in a mouse model of premature aging.

Curley M, Milne L, Smith S, Jørgensen A, Frederiksen H, Hadoke P, Potter P, Smith LB. Curley M, et al. Among authors: smith s, smith lb. FASEB J. 2019 Jan;33(1):978-995. doi: 10.1096/fj.201800612R. Epub 2018 Aug 6. FASEB J. 2019. PMID: 30080443 Free PMC article.

We conclude that age-related LC dysfunction is largely driven by aging of the supporting testicular microenvironment.-Curley, M., Milne, L., Smith, S., Jorgensen, A., Frederiksen, H., Hadoke, P., Potter, P., Smith, L. ...

We conclude that age-related LC dysfunction is largely driven by aging of the supporting testicular microenvironment.-Curley, M., Milne, L., …

6

Relationship of transcriptional markers to Leydig cell number in the mouse testis.

Rebourcet D, Monteiro A, Cruickshanks L, Jeffery N, Smith S, Milne L, O'Shaughnessy PJ, Smith LB. Rebourcet D, et al. Among authors: smith s, smith lb. PLoS One. 2019 Jul 10;14(7):e0219524. doi: 10.1371/journal.pone.0219524. eCollection 2019. PLoS One. 2019. PMID: 31291327 Free PMC article.

7

Androgen receptor signalling in the male adrenal facilitates X-zone regression, cell turnover and protects against adrenal degeneration during ageing.

Gannon AL, O'Hara L, Mason JI, Jørgensen A, Frederiksen H, Milne L, Smith S, Mitchell RT, Smith LB. Gannon AL, et al. Among authors: smith s, smith lb. Sci Rep. 2019 Jul 18;9(1):10457. doi: 10.1038/s41598-019-46049-3. Sci Rep. 2019. PMID: 31320667 Free PMC article.

8

Androgen Receptor Is Dispensable for X-Zone Regression in the Female Adrenal but Regulates Post-Partum Corticosterone Levels and Protects Cortex Integrity.

Gannon AL, O'Hara L, Mason IJ, Jørgensen A, Frederiksen H, Curley M, Milne L, Smith S, Mitchell RT, Smith LB. Gannon AL, et al. Among authors: smith s, smith lb. Front Endocrinol (Lausanne). 2021 Jan 21;11:599869. doi: 10.3389/fendo.2020.599869. eCollection 2020. Front Endocrinol (Lausanne). 2021. PMID: 33584538 Free PMC article.

9

Sertoli Cells Modulate Testicular Vascular Network Development, Structure, and Function to Influence Circulating Testosterone Concentrations in Adult Male Mice.

Rebourcet D, Wu J, Cruickshanks L, Smith SE, Milne L, Fernando A, Wallace RJ, Gray CD, Hadoke PW, Mitchell RT, O'Shaughnessy PJ, Smith LB. Rebourcet D, et al. Endocrinology. 2016 Jun;157(6):2479-88. doi: 10.1210/en.2016-1156. Epub 2016 May 4. Endocrinology. 2016. PMID: 27145015 Free PMC article.

10

Sertoli cell androgen receptor signalling in adulthood is essential for post-meiotic germ cell development.

Willems A, Roesl C, Mitchell RT, Milne L, Jeffery N, Smith S, Verhoeven G, Brown P, Smith LB. Willems A, et al. Among authors: smith s, smith lb. Mol Reprod Dev. 2015 Sep;82(9):626-7. doi: 10.1002/mrd.22506. Epub 2015 Jun 9. Mol Reprod Dev. 2015. PMID: 26061432 Free PMC article. No abstract available.

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