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A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane proteins.
Chae PS, Rasmussen SG, Rana RR, Gotfryd K, Kruse AC, Manglik A, Cho KH, Nurva S, Gether U, Guan L, Loland CJ, Byrne B, Kobilka BK, Gellman SH. Chae PS, et al. Among authors: loland cj. Chemistry. 2012 Jul 27;18(31):9485-90. doi: 10.1002/chem.201200069. Epub 2012 Jun 22. Chemistry. 2012. PMID: 22730191 Free PMC article. No abstract available.
Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins.
Chae PS, Rasmussen SG, Rana RR, Gotfryd K, Chandra R, Goren MA, Kruse AC, Nurva S, Loland CJ, Pierre Y, Drew D, Popot JL, Picot D, Fox BG, Guan L, Gether U, Byrne B, Kobilka B, Gellman SH. Chae PS, et al. Among authors: loland cj. Nat Methods. 2010 Dec;7(12):1003-8. doi: 10.1038/nmeth.1526. Epub 2010 Oct 31. Nat Methods. 2010. PMID: 21037590 Free PMC article.
Tandem facial amphiphiles for membrane protein stabilization.
Chae PS, Gotfryd K, Pacyna J, Miercke LJ, Rasmussen SG, Robbins RA, Rana RR, Loland CJ, Kobilka B, Stroud R, Byrne B, Gether U, Gellman SH. Chae PS, et al. Among authors: loland cj. J Am Chem Soc. 2010 Dec 1;132(47):16750-2. doi: 10.1021/ja1072959. Epub 2010 Nov 4. J Am Chem Soc. 2010. PMID: 21049926 Free PMC article.
Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study.
Chae PS, Rana RR, Gotfryd K, Rasmussen SG, Kruse AC, Cho KH, Capaldi S, Carlsson E, Kobilka B, Loland CJ, Gether U, Banerjee S, Byrne B, Lee JK, Gellman SH. Chae PS, et al. Among authors: loland cj. Chem Commun (Camb). 2013 Mar 21;49(23):2287-9. doi: 10.1039/c2cc36844g. Chem Commun (Camb). 2013. PMID: 23165475 Free PMC article.
111 results