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2-Substituted α,β-Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes.
Bhattarai S, Pippel J, Scaletti E, Idris R, Freundlieb M, Rolshoven G, Renn C, Lee SY, Abdelrahman A, Zimmermann H, El-Tayeb A, Müller CE, Sträter N. Bhattarai S, et al. Among authors: el tayeb a. J Med Chem. 2020 Mar 26;63(6):2941-2957. doi: 10.1021/acs.jmedchem.9b01611. Epub 2020 Feb 28. J Med Chem. 2020. PMID: 32045236
Extracellular adenosine reversibly inhibits the activation of human regulatory T cells and negatively influences the achievement of the operational tolerance in liver transplantation.
Baroja-Mazo A, Revilla-Nuin B, de Bejar Á, Martínez-Alarcón L, Herrero JI, El-Tayeb A, Müller CE, Aparicio P, Pelegrín P, Pons JA. Baroja-Mazo A, et al. Among authors: el tayeb a. Am J Transplant. 2019 Jan;19(1):48-61. doi: 10.1111/ajt.15023. Epub 2018 Aug 31. Am J Transplant. 2019. PMID: 30019408 Free PMC article.
Adenosine A2A receptor agonists with potent antiplatelet activity.
Fuentes E, Fuentes M, Caballero J, Palomo I, Hinz S, El-Tayeb A, Müller CE. Fuentes E, et al. Among authors: el tayeb a. Platelets. 2018 May;29(3):292-300. doi: 10.1080/09537104.2017.1306043. Epub 2017 May 15. Platelets. 2018. PMID: 28504052
52 results