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Synthesis and biological activity of 11-Oxygenated and heterocyclic estrone analogs in pancreatic cancer monolayers and 3D spheroids.
Bioorg Med Chem. 2024 Apr 1;103:117678. doi: 10.1016/j.bmc.2024.117678. Epub 2024 Mar 5.
Bioorg Med Chem. 2024.
PMID: 38489997
Deacetylated Sialic Acid Sensitizes Lung and Colon Cancers to Novel Cucurbitacin-Inspired Estrone Epidermal Growth Factor Receptor (EGFR) Inhibitor Analogs.
Anim MT, Tuffour I, Willis R, Schell M, Ostlund T, Mahnashi MH, Halaweish F, Willand-Charnley R.
Anim MT, et al. Among authors: ostlund t.
Molecules. 2023 Aug 26;28(17):6257. doi: 10.3390/molecules28176257.
Molecules. 2023.
PMID: 37687086
Free PMC article.
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Antiproliferation and apoptosis studies of estrone pharmacophores in triple-negative breast cancer.
Acheampong F, Ostlund T, Mahnashi M, Halaweish F.
Acheampong F, et al. Among authors: ostlund t.
Chem Biol Drug Des. 2023 Nov;102(5):1050-1066. doi: 10.1111/cbdd.14303. Epub 2023 Jul 27.
Chem Biol Drug Des. 2023.
PMID: 37500540
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Estrone analogs as potential inhibitors targeting EGFR-MAPK pathway in non-small-cell lung cancer.
Acheampong F, Ostlund T, Mahnashi M, Halaweish F.
Acheampong F, et al. Among authors: ostlund t.
Chem Biol Drug Des. 2023 Jun;101(6):1356-1366. doi: 10.1111/cbdd.14218. Epub 2023 Feb 24.
Chem Biol Drug Des. 2023.
PMID: 36775996
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Novel EGFR-MAPK kinase and ABC transporter inhibitors for HepG2 resistant to Erlotinib.
Ostlund T, SutraDhar K, Elgazwi SM, Mahnashi M, Kyeremateng J, Iram S, Halaweish F.
Ostlund T, et al.
Drug Dev Res. 2023 Apr;84(2):200-210. doi: 10.1002/ddr.22023. Epub 2022 Dec 9.
Drug Dev Res. 2023.
PMID: 36484285
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Triazole-estradiol analogs: A potential cancer therapeutic targeting ovarian and colorectal cancer.
Ostlund T, Alotaibi F, Kyeremateng J, Halaweish H, Kasten A, Iram S, Halaweish F.
Ostlund T, et al.
Steroids. 2022 Jan;177:108950. doi: 10.1016/j.steroids.2021.108950. Epub 2021 Dec 18.
Steroids. 2022.
PMID: 34933058
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