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A cohesin traffic pattern genetically linked to gene regulation.
Valton AL, Venev SV, Mair B, Khokhar ES, Tong AHY, Usaj M, Chan K, Pai AA, Moffat J, Dekker J. Valton AL, et al. Among authors: moffat j. Nat Struct Mol Biol. 2022 Dec;29(12):1239-1251. doi: 10.1038/s41594-022-00890-9. Epub 2022 Dec 8. Nat Struct Mol Biol. 2022. PMID: 36482254 Free PMC article.
Global Genetic Networks and the Genotype-to-Phenotype Relationship.
Costanzo M, Kuzmin E, van Leeuwen J, Mair B, Moffat J, Boone C, Andrews B. Costanzo M, et al. Among authors: moffat j. Cell. 2019 Mar 21;177(1):85-100. doi: 10.1016/j.cell.2019.01.033. Cell. 2019. PMID: 30901552 Free PMC article. Review.
Genetic interaction networks in cancer cells.
Mair B, Moffat J, Boone C, Andrews BJ. Mair B, et al. Among authors: moffat j. Curr Opin Genet Dev. 2019 Feb;54:64-72. doi: 10.1016/j.gde.2019.03.002. Epub 2019 Apr 8. Curr Opin Genet Dev. 2019. PMID: 30974317 Free PMC article. Review.
CRISPR screens are feasible in TP53 wild-type cells.
Brown KR, Mair B, Soste M, Moffat J. Brown KR, et al. Among authors: moffat j. Mol Syst Biol. 2019 Aug;15(8):e8679. doi: 10.15252/msb.20188679. Mol Syst Biol. 2019. PMID: 31464370 Free PMC article.
High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting.
Mair B, Aldridge PM, Atwal RS, Philpott D, Zhang M, Masud SN, Labib M, Tong AHY, Sargent EH, Angers S, Moffat J, Kelley SO. Mair B, et al. Among authors: moffat j. Nat Biomed Eng. 2019 Oct;3(10):796-805. doi: 10.1038/s41551-019-0454-8. Epub 2019 Sep 23. Nat Biomed Eng. 2019. PMID: 31548591
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.
Aregger M, Lawson KA, Billmann M, Costanzo M, Tong AHY, Chan K, Rahman M, Brown KR, Ross C, Usaj M, Nedyalkova L, Sizova O, Habsid A, Pawling J, Lin ZY, Abdouni H, Wong CJ, Weiss A, Mero P, Dennis JW, Gingras AC, Myers CL, Andrews BJ, Boone C, Moffat J. Aregger M, et al. Among authors: moffat j. Nat Metab. 2020 Jun;2(6):499-513. doi: 10.1038/s42255-020-0211-z. Epub 2020 Jun 1. Nat Metab. 2020. PMID: 32694731 Free PMC article.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.
Lawson KA, Sousa CM, Zhang X, Kim E, Akthar R, Caumanns JJ, Yao Y, Mikolajewicz N, Ross C, Brown KR, Zid AA, Fan ZP, Hui S, Krall JA, Simons DM, Slater CJ, De Jesus V, Tang L, Singh R, Goldford JE, Martin S, Huang Q, Francis EA, Habsid A, Climie R, Tieu D, Wei J, Li R, Tong AHY, Aregger M, Chan KS, Han H, Wang X, Mero P, Brumell JH, Finelli A, Ailles L, Bader G, Smolen GA, Kingsbury GA, Hart T, Kung C, Moffat J. Lawson KA, et al. Among authors: moffat j. Nature. 2020 Oct;586(7827):120-126. doi: 10.1038/s41586-020-2746-2. Epub 2020 Sep 23. Nature. 2020. PMID: 32968282 Free PMC article.
467 results