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Lactobacillus rhamnosus GG increases cyclooxygenase-2 expression and prostaglandin E2 secretion in colonic myofibroblasts via a MyD88-dependent mechanism during homeostasis.
Uribe G, Villéger R, Bressollier P, Dillard RN, Worthley DL, Wang TC, Powell DW, Urdaci MC, Pinchuk IV. Uribe G, et al. Among authors: villeger r. Cell Microbiol. 2018 Nov;20(11):e12871. doi: 10.1111/cmi.12871. Epub 2018 Jul 26. Cell Microbiol. 2018. PMID: 29920917 Free PMC article.
Matrix metalloproteinases cleave membrane-bound PD-L1 on CD90+ (myo-)fibroblasts in Crohn's disease and regulate Th1/Th17 cell responses.
Aguirre JE, Beswick EJ, Grim C, Uribe G, Tafoya M, Chacon Palma G, Samedi V, McKee R, Villeger R, Fofanov Y, Cong Y, Yochum G, Koltun W, Powell D, Pinchuk IV. Aguirre JE, et al. Among authors: villeger r. Int Immunol. 2020 Jan 9;32(1):57-68. doi: 10.1093/intimm/dxz060. Int Immunol. 2020. PMID: 31633754 Free PMC article.
Deletion of cystathionine-γ-lyase in bone marrow-derived cells promotes colitis-associated carcinogenesis.
Thanki KK, Johnson P, Higgins EJ, Maskey M, Phillips C, Dash S, Almenas FA, Govar AA, Tian B, Villéger R, Beswick E, Wang R, Szabo C, Chao C, Pinchuk IV, Hellmich MR, Módis K. Thanki KK, et al. Among authors: villeger r. Redox Biol. 2022 Sep;55:102417. doi: 10.1016/j.redox.2022.102417. Epub 2022 Jul 21. Redox Biol. 2022. PMID: 35933902 Free PMC article.
Colibactin-positive Escherichia coli induce a procarcinogenic immune environment leading to immunotherapy resistance in colorectal cancer.
Lopès A, Billard E, Casse AH, Villéger R, Veziant J, Roche G, Carrier G, Sauvanet P, Briat A, Pagès F, Naimi S, Pezet D, Barnich N, Dumas B, Bonnet M. Lopès A, et al. Among authors: villeger r. Int J Cancer. 2020 Jun 1;146(11):3147-3159. doi: 10.1002/ijc.32920. Epub 2020 Mar 10. Int J Cancer. 2020. PMID: 32037530 Free article.
Increased activity of MAPKAPK2 within mesenchymal cells as a target for inflammation associated fibrosis in Crohn's Disease.
Chulkina M, Rohmer C, McAninch S, Panganiban RP, Villéger R, Portolese A, Ciocirlan J, Yang W, Cohen C, Koltun W, Valentine JF, Cong Y, Yochum G, Beswick EJ, Pinchuk IV. Chulkina M, et al. Among authors: villeger r. J Crohns Colitis. 2024 Jan 15:jjae009. doi: 10.1093/ecco-jcc/jjae009. Online ahead of print. J Crohns Colitis. 2024. PMID: 38224550
Effect of endocrine disruptors on bacterial virulence.
Thiroux A, Berjeaud JM, Villéger R, Crépin A. Thiroux A, et al. Among authors: villeger r. Front Cell Infect Microbiol. 2023 Nov 6;13:1292233. doi: 10.3389/fcimb.2023.1292233. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 38029256 Free PMC article. Review.
18 results