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Human iPSC-hepatocyte modeling of alpha-1 antitrypsin heterozygosity reveals metabolic dysregulation and cellular heterogeneity.
Kaserman JE, Werder RB, Wang F, Matte T, Higgins MI, Dodge M, Lindstrom-Vautrin J, Bawa P, Hinds A, Bullitt E, Caballero IS, Shi X, Gerszten RE, Brunetti-Pierri N, Liesa M, Villacorta-Martin C, Hollenberg AN, Kotton DN, Wilson AA. Kaserman JE, et al. Among authors: hollenberg an. Cell Rep. 2022 Dec 6;41(10):111775. doi: 10.1016/j.celrep.2022.111775. Cell Rep. 2022. PMID: 36476855 Free PMC article.
International Union of Basic and Clinical Pharmacology CXIII: Nuclear Receptor Superfamily-Update 2023.
Burris TP, de Vera IMS, Cote I, Flaveny CA, Wanninayake US, Chatterjee A, Walker JK, Steinauer N, Zhang J, Coons LA, Korach KS, Cain DW, Hollenberg AN, Webb P, Forrest D, Jetten AM, Edwards DP, Grimm SL, Hartig S, Lange CA, Richer JK, Sartorius CA, Tetel M, Billon C, Elgendy B, Hegazy L, Griffett K, Peinetti N, Burnstein KL, Hughes TS, Sitaula S, Stayrook KR, Culver A, Murray MH, Finck BN, Cidlowski JA. Burris TP, et al. Among authors: hollenberg an. Pharmacol Rev. 2023 Nov;75(6):1233-1318. doi: 10.1124/pharmrev.121.000436. Epub 2023 Aug 16. Pharmacol Rev. 2023. PMID: 37586884 Free PMC article. Review.
Thyroid hormone signaling promotes hepatic lipogenesis through the transcription factor ChREBP.
Mendoza A, Tang C, Choi J, Acuña M, Logan M, Martin AG, Al-Sowaimel L, Desai BN, Tenen DE, Jacobs C, Lyubetskaya A, Fu Y, Liu H, Tsai L, Cohen DE, Forrest D, Wilson AA, Hollenberg AN. Mendoza A, et al. Among authors: hollenberg an. Sci Signal. 2021 Nov 16;14(709):eabh3839. doi: 10.1126/scisignal.abh3839. Epub 2021 Nov 16. Sci Signal. 2021. PMID: 34784250 Free PMC article.
124 results