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Optimized ACE2 decoys neutralize antibody-resistant SARS-CoV-2 variants through functional receptor mimicry and treat infection in vivo.
Torchia JA, Tavares AH, Carstensen LS, Chen DY, Huang J, Xiao T, Mukherjee S, Reeves PM, Tu H, Sluder AE, Chen B, Kotton DN, Bowen RA, Saeed M, Poznansky MC, Freeman GJ. Torchia JA, et al. Among authors: xiao t. Sci Adv. 2022 Dec 9;8(49):eabq6527. doi: 10.1126/sciadv.abq6527. Epub 2022 Dec 7. Sci Adv. 2022. PMID: 36475798 Free PMC article.
Distinct conformational states of SARS-CoV-2 spike protein.
Cai Y, Zhang J, Xiao T, Peng H, Sterling SM, Walsh RM Jr, Rawson S, Rits-Volloch S, Chen B. Cai Y, et al. Among authors: xiao t. Science. 2020 Sep 25;369(6511):1586-1592. doi: 10.1126/science.abd4251. Epub 2020 Jul 21. Science. 2020. PMID: 32694201 Free PMC article.
Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor.
Zhao P, Praissman JL, Grant OC, Cai Y, Xiao T, Rosenbalm KE, Aoki K, Kellman BP, Bridger R, Barouch DH, Brindley MA, Lewis NE, Tiemeyer M, Chen B, Woods RJ, Wells L. Zhao P, et al. Among authors: xiao t. bioRxiv [Preprint]. 2020 Jul 24:2020.06.25.172403. doi: 10.1101/2020.06.25.172403. bioRxiv. 2020. PMID: 32743578 Free PMC article. Updated. Preprint.
Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor.
Zhao P, Praissman JL, Grant OC, Cai Y, Xiao T, Rosenbalm KE, Aoki K, Kellman BP, Bridger R, Barouch DH, Brindley MA, Lewis NE, Tiemeyer M, Chen B, Woods RJ, Wells L. Zhao P, et al. Among authors: xiao t. Cell Host Microbe. 2020 Oct 7;28(4):586-601.e6. doi: 10.1016/j.chom.2020.08.004. Epub 2020 Aug 24. Cell Host Microbe. 2020. PMID: 32841605 Free PMC article.
A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent.
Xiao T, Lu J, Zhang J, Johnson RI, McKay LGA, Storm N, Lavine CL, Peng H, Cai Y, Rits-Volloch S, Lu S, Quinlan BD, Farzan M, Seaman MS, Griffiths A, Chen B. Xiao T, et al. Nat Struct Mol Biol. 2021 Feb;28(2):202-209. doi: 10.1038/s41594-020-00549-3. Epub 2021 Jan 11. Nat Struct Mol Biol. 2021. PMID: 33432247 Free PMC article.
Structural impact on SARS-CoV-2 spike protein by D614G substitution.
Zhang J, Cai Y, Xiao T, Lu J, Peng H, Sterling SM, Walsh RM Jr, Rits-Volloch S, Zhu H, Woosley AN, Yang W, Sliz P, Chen B. Zhang J, et al. Among authors: xiao t. Science. 2021 Apr 30;372(6541):525-530. doi: 10.1126/science.abf2303. Epub 2021 Mar 16. Science. 2021. PMID: 33727252 Free PMC article.
HIV-1 Entry and Membrane Fusion Inhibitors.
Xiao T, Cai Y, Chen B. Xiao T, et al. Viruses. 2021 Apr 23;13(5):735. doi: 10.3390/v13050735. Viruses. 2021. PMID: 33922579 Free PMC article. Review.
Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants.
Cai Y, Zhang J, Xiao T, Lavine CL, Rawson S, Peng H, Zhu H, Anand K, Tong P, Gautam A, Lu S, Sterling SM, Walsh RM Jr, Rits-Volloch S, Lu J, Wesemann DR, Yang W, Seaman MS, Chen B. Cai Y, et al. Among authors: xiao t. Science. 2021 Aug 6;373(6555):642-648. doi: 10.1126/science.abi9745. Epub 2021 Jun 24. Science. 2021. PMID: 34168070 Free PMC article.
Structure of SARS-CoV-2 spike protein.
Zhang J, Xiao T, Cai Y, Chen B. Zhang J, et al. Among authors: xiao t. Curr Opin Virol. 2021 Oct;50:173-182. doi: 10.1016/j.coviro.2021.08.010. Epub 2021 Sep 8. Curr Opin Virol. 2021. PMID: 34534731 Free PMC article. Review.
2,725 results