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Targeting the tubulin C-terminal tail by charged small molecules.
Li S, Mori M, Yang M, Elfazazi S, Hortigüela R, Chan P, Feng X, Risinger A, Yang Z, Oliva MÁ, Fernando Díaz J, Fang WS. Li S, et al. Among authors: chan p. Org Biomol Chem. 2022 Dec 21;21(1):153-162. doi: 10.1039/d2ob01910h. Org Biomol Chem. 2022. PMID: 36472095
[No title available]
[No authors listed] [No authors listed] PMID: 35556797
Modulation of taxane binding to tubulin curved and straight conformations by systematic 3'N modification provides for improved microtubule binding, persistent cytotoxicity and in vivo potency.
Ma Y, Josa-Prado F, Essif JN, Liu S, Li S, Lucena-Agell D, Chan PY, Goossens K, Hortigüela R, Matesanz R, Wang Y, Gago F, Wang H, Risinger A, Diaz JF, Fang WS. Ma Y, et al. Eur J Med Chem. 2023 Nov 5;259:115668. doi: 10.1016/j.ejmech.2023.115668. Epub 2023 Jul 19. Eur J Med Chem. 2023. PMID: 37490800
Generalizable Approach to Quantifying Guideline-Directed Medical Therapy.
Khan MS, Chan PS, Sherrod CF, Ikemura N, Sauer AJ, Jones PG, Fonarow GC, Butler J, DeVore AD, Lund LH, Spertus JA. Khan MS, et al. Among authors: chan ps. Circ Heart Fail. 2024 May;17(5):e011164. doi: 10.1161/CIRCHEARTFAILURE.123.011164. Epub 2024 May 14. Circ Heart Fail. 2024. PMID: 38742418 Review.
5,355 results