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Cohesin and CTCF control the dynamics of chromosome folding.
Mach P, Kos PI, Zhan Y, Cramard J, Gaudin S, Tünnermann J, Marchi E, Eglinger J, Zuin J, Kryzhanovska M, Smallwood S, Gelman L, Roth G, Nora EP, Tiana G, Giorgetti L. Mach P, et al. Among authors: zhan y. Nat Genet. 2022 Dec;54(12):1907-1918. doi: 10.1038/s41588-022-01232-7. Epub 2022 Dec 5. Nat Genet. 2022. PMID: 36471076 Free PMC article.
DamC reveals principles of chromatin folding in vivo without crosslinking and ligation.
Redolfi J, Zhan Y, Valdes-Quezada C, Kryzhanovska M, Guerreiro I, Iesmantavicius V, Pollex T, Grand RS, Mulugeta E, Kind J, Tiana G, Smallwood SA, de Laat W, Giorgetti L. Redolfi J, et al. Among authors: zhan y. Nat Struct Mol Biol. 2019 Jun;26(6):471-480. doi: 10.1038/s41594-019-0231-0. Epub 2019 May 27. Nat Struct Mol Biol. 2019. PMID: 31133702 Free PMC article.
The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist.
van Bemmel JG, Galupa R, Gard C, Servant N, Picard C, Davies J, Szempruch AJ, Zhan Y, Żylicz JJ, Nora EP, Lameiras S, de Wit E, Gentien D, Baulande S, Giorgetti L, Guttman M, Hughes JR, Higgs DR, Gribnau J, Heard E. van Bemmel JG, et al. Among authors: zhan y. Nat Genet. 2019 Jun;51(6):1024-1034. doi: 10.1038/s41588-019-0412-0. Epub 2019 May 27. Nat Genet. 2019. PMID: 31133748 Free PMC article.
A Conserved Noncoding Locus Regulates Random Monoallelic Xist Expression across a Topological Boundary.
Galupa R, Nora EP, Worsley-Hunt R, Picard C, Gard C, van Bemmel JG, Servant N, Zhan Y, El Marjou F, Johanneau C, Diabangouaya P, Le Saux A, Lameiras S, Pipoli da Fonseca J, Loos F, Gribnau J, Baulande S, Ohler U, Giorgetti L, Heard E. Galupa R, et al. Among authors: zhan y. Mol Cell. 2020 Jan 16;77(2):352-367.e8. doi: 10.1016/j.molcel.2019.10.030. Epub 2019 Nov 20. Mol Cell. 2020. PMID: 31759823 Free PMC article.
4,298 results