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Reimagining scientific conferences-a Keystone Symposia report.
Weiman S, Cable J, Greenleaf W, Rundel F, Whitfield KE, Wingate L, Gallagher R, Pesanelli J, Orr D, Jarvis TC, Cadar R, Uva M, Ruediger D, Vaez R, Frisby A, Ahmed S, Donoviel D, Klinman J, Johnson D. Weiman S, et al. Among authors: jarvis tc. Ann N Y Acad Sci. 2023 Sep;1527(1):49-59. doi: 10.1111/nyas.15037. Epub 2023 Aug 3. Ann N Y Acad Sci. 2023. PMID: 37534923
Microbiological profile, preclinical pharmacokinetics and efficacy of CRS0393, a novel antimycobacterial agent targeting MmpL3.
Ochsner UA, De Groote MA, Jarvis TC, Liu H, Youmans T, Hoang T, Ribble W, Day J, Li W, Pearce C, Walz A, Panthi CM, Rimal B, Stevens CM, Zgurskaya HI, Jackson M, Ordway D, Gonzalez-Juarrero M, Sun X, Lamichhane G, Mason C. Ochsner UA, et al. Among authors: jarvis tc. Tuberculosis (Edinb). 2023 Jan;138:102288. doi: 10.1016/j.tube.2022.102288. Epub 2022 Nov 29. Tuberculosis (Edinb). 2023. PMID: 36470124 Free PMC article.
Multiple-Ascending-Dose Phase 1 Clinical Study of the Safety, Tolerability, and Pharmacokinetics of CRS3123, a Narrow-Spectrum Agent with Minimal Disruption of Normal Gut Microbiota.
Lomeli BK, Galbraith H, Schettler J, Saviolakis GA, El-Amin W, Osborn B, Ravel J, Hazleton K, Lozupone CA, Evans RJ, Bell SJ, Ochsner UA, Jarvis TC, Baqar S, Janjic N. Lomeli BK, et al. Among authors: jarvis tc. Antimicrob Agents Chemother. 2019 Dec 20;64(1):e01395-19. doi: 10.1128/AAC.01395-19. Print 2019 Dec 20. Antimicrob Agents Chemother. 2019. PMID: 31685472 Free PMC article. Clinical Trial.
Safety, Tolerability, Systemic Exposure, and Metabolism of CRS3123, a Methionyl-tRNA Synthetase Inhibitor Developed for Treatment of Clostridium difficile, in a Phase 1 Study.
Nayak SU, Griffiss JM, Blumer J, O'Riordan MA, Gray W, McKenzie R, Jurao RA, An AT, Le M, Bell SJ, Ochsner UA, Jarvis TC, Janjic N, Zenilman JM. Nayak SU, et al. Among authors: jarvis tc. Antimicrob Agents Chemother. 2017 Jul 25;61(8):e02760-16. doi: 10.1128/AAC.02760-16. Print 2017 Aug. Antimicrob Agents Chemother. 2017. PMID: 28584140 Free PMC article. Clinical Trial.
Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor.
Jarvis TC, Davies DR, Hisaminato A, Resnicow DI, Gupta S, Waugh SM, Nagabukuro A, Wadatsu T, Hishigaki H, Gawande B, Zhang C, Wolk SK, Mayfield WS, Nakaishi Y, Burgin AB, Stewart LJ, Edwards TE, Gelinas AD, Schneider DJ, Janjic N. Jarvis TC, et al. Structure. 2015 Jul 7;23(7):1293-304. doi: 10.1016/j.str.2015.03.027. Epub 2015 May 28. Structure. 2015. PMID: 26027732 Free article.
Crystal structure of interleukin-6 in complex with a modified nucleic acid ligand.
Gelinas AD, Davies DR, Edwards TE, Rohloff JC, Carter JD, Zhang C, Gupta S, Ishikawa Y, Hirota M, Nakaishi Y, Jarvis TC, Janjic N. Gelinas AD, et al. Among authors: jarvis tc. J Biol Chem. 2014 Mar 21;289(12):8720-34. doi: 10.1074/jbc.M113.532697. Epub 2014 Jan 12. J Biol Chem. 2014. PMID: 24415767 Free PMC article.
Chemically modified DNA aptamers bind interleukin-6 with high affinity and inhibit signaling by blocking its interaction with interleukin-6 receptor.
Gupta S, Hirota M, Waugh SM, Murakami I, Suzuki T, Muraguchi M, Shibamori M, Ishikawa Y, Jarvis TC, Carter JD, Zhang C, Gawande B, Vrkljan M, Janjic N, Schneider DJ. Gupta S, et al. Among authors: jarvis tc. J Biol Chem. 2014 Mar 21;289(12):8706-19. doi: 10.1074/jbc.M113.532580. Epub 2014 Jan 12. J Biol Chem. 2014. PMID: 24415766 Free PMC article.
37 results