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The A2B adenosine receptor modulates pulmonary hypertension associated with interstitial lung disease.
Karmouty-Quintana H, Zhong H, Acero L, Weng T, Melicoff E, West JD, Hemnes A, Grenz A, Eltzschig HK, Blackwell TS, Xia Y, Johnston RA, Zeng D, Belardinelli L, Blackburn MR. Karmouty-Quintana H, et al. Among authors: eltzschig hk. FASEB J. 2012 Jun;26(6):2546-57. doi: 10.1096/fj.11-200907. Epub 2012 Mar 13. FASEB J. 2012. PMID: 22415303 Free PMC article.
Elevated ecto-5'-nucleotidase-mediated increased renal adenosine signaling via A2B adenosine receptor contributes to chronic hypertension.
Zhang W, Zhang Y, Wang W, Dai Y, Ning C, Luo R, Sun K, Glover L, Grenz A, Sun H, Tao L, Zhang W, Colgan SP, Blackburn MR, Eltzschig HK, Kellems RE, Xia Y. Zhang W, et al. Among authors: eltzschig hk. Circ Res. 2013 May 24;112(11):1466-78. doi: 10.1161/CIRCRESAHA.111.300166. Epub 2013 Apr 12. Circ Res. 2013. PMID: 23584256 Free PMC article.
CD73-dependent generation of adenosine and endothelial Adora2b signaling attenuate diabetic nephropathy.
Tak E, Ridyard D, Kim JH, Zimmerman M, Werner T, Wang XX, Shabeka U, Seo SW, Christians U, Klawitter J, Moldovan R, Garcia G, Levi M, Haase V, Ravid K, Eltzschig HK, Grenz A. Tak E, et al. Among authors: eltzschig hk. J Am Soc Nephrol. 2014 Mar;25(3):547-63. doi: 10.1681/ASN.2012101014. Epub 2013 Nov 21. J Am Soc Nephrol. 2014. PMID: 24262796 Free PMC article.
Deletion of ADORA2B from myeloid cells dampens lung fibrosis and pulmonary hypertension.
Karmouty-Quintana H, Philip K, Acero LF, Chen NY, Weng T, Molina JG, Luo F, Davies J, Le NB, Bunge I, Volcik KA, Le TT, Johnston RA, Xia Y, Eltzschig HK, Blackburn MR. Karmouty-Quintana H, et al. Among authors: eltzschig hk. FASEB J. 2015 Jan;29(1):50-60. doi: 10.1096/fj.14-260182. Epub 2014 Oct 15. FASEB J. 2015. PMID: 25318478 Free PMC article.
313 results