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Viral proteases as therapeutic targets.
Majerová T, Konvalinka J. Majerová T, et al. Among authors: konvalinka j. Mol Aspects Med. 2022 Dec;88:101159. doi: 10.1016/j.mam.2022.101159. Epub 2022 Nov 29. Mol Aspects Med. 2022. PMID: 36459838 Free PMC article. Review.
Unusual binding mode of an HIV-1 protease inhibitor explains its potency against multi-drug-resistant virus strains.
Weber J, Mesters JR, Lepsík M, Prejdová J, Svec M, Sponarová J, Mlcochová P, Skalická K, Strísovský K, Uhlíková T, Soucek M, Machala L, Stanková M, Vondrásek J, Klimkait T, Kraeusslich HG, Hilgenfeld R, Konvalinka J. Weber J, et al. Among authors: konvalinka j. J Mol Biol. 2002 Dec 6;324(4):739-54. doi: 10.1016/s0022-2836(02)01139-7. J Mol Biol. 2002. PMID: 12460574
Retroviral proteases and their roles in virion maturation.
Konvalinka J, Kräusslich HG, Müller B. Konvalinka J, et al. Virology. 2015 May;479-480:403-17. doi: 10.1016/j.virol.2015.03.021. Epub 2015 Mar 26. Virology. 2015. PMID: 25816761 Free article. Review.
Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery.
Kryštůfek R, Šácha P, Starková J, Brynda J, Hradilek M, Tloušt'ová E, Grzymska J, Rut W, Boucher MJ, Drąg M, Majer P, Hájek M, Řezáčová P, Madhani HD, Craik CS, Konvalinka J. Kryštůfek R, et al. Among authors: konvalinka j. J Med Chem. 2021 May 27;64(10):6706-6719. doi: 10.1021/acs.jmedchem.0c02177. Epub 2021 May 18. J Med Chem. 2021. PMID: 34006103 Free PMC article.
146 results