Povstyan OV - Search Results

1

Improved PIEZO1 agonism through 4-benzoic acid modification of Yoda1.

Parsonage G, Cuthbertson K, Endesh N, Murciano N, Hyman AJ, Revill CH, Povstyan OV, Chuntharpursat-Bon E, Debant M, Ludlow MJ, Futers TS, Lichtenstein L, Kinsella JA, Bartoli F, Rotordam MG, Becker N, Brüggemann A, Foster R, Beech DJ. Parsonage G, et al. Among authors: povstyan ov. Br J Pharmacol. 2023 Aug;180(16):2039-2063. doi: 10.1111/bph.15996. Epub 2023 Jan 31. Br J Pharmacol. 2023. PMID: 36457143 Free PMC article.

2

[No title available]

[No authors listed] [No authors listed] PMID: 36784014

3

PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing.

Chuntharpursat-Bon E, Povstyan OV, Ludlow MJ, Carrier DJ, Debant M, Shi J, Gaunt HJ, Bauer CC, Curd A, Simon Futers T, Baxter PD, Peckham M, Muench SP, Adamson A, Humphreys N, Tumova S, Bon RS, Cubbon R, Lichtenstein L, Beech DJ. Chuntharpursat-Bon E, et al. Among authors: povstyan ov. Commun Biol. 2023 Apr 1;6(1):358. doi: 10.1038/s42003-023-04706-4. Commun Biol. 2023. PMID: 37005489 Free PMC article.

4

Modeling of full-length Piezo1 suggests importance of the proximal N-terminus for dome structure.

Chong J, De Vecchis D, Hyman AJ, Povstyan OV, Ludlow MJ, Shi J, Beech DJ, Kalli AC. Chong J, et al. Among authors: povstyan ov. Biophys J. 2021 Apr 20;120(8):1343-1356. doi: 10.1016/j.bpj.2021.02.003. Epub 2021 Feb 12. Biophys J. 2021. PMID: 33582137 Free PMC article.

5

RBCs prevent rapid PIEZO1 inactivation and expose slow deactivation as a mechanism of dehydrated hereditary stomatocytosis.

Evans EL, Povstyan OV, De Vecchis D, Macrae F, Lichtenstein L, Futers TS, Parsonage G, Humphreys NE, Adamson A, Kalli AC, Ludlow MJ, Beech DJ. Evans EL, et al. Among authors: povstyan ov. Blood. 2020 Jul 2;136(1):140-144. doi: 10.1182/blood.2019004174. Blood. 2020. PMID: 32305040 Free PMC article. No abstract available.

6

Synergistic interplay of Gβγ and phosphatidylinositol 4,5-bisphosphate dictates Kv7.4 channel activity.

Povstyan OV, Barrese V, Stott JB, Greenwood IA. Povstyan OV, et al. Pflugers Arch. 2017 Feb;469(2):213-223. doi: 10.1007/s00424-016-1916-4. Epub 2016 Dec 15. Pflugers Arch. 2017. PMID: 27981364 Free PMC article.

7

MicroRNA-153 targeting of KCNQ4 contributes to vascular dysfunction in hypertension.

Carr G, Barrese V, Stott JB, Povstyan OV, Jepps TA, Figueiredo HB, Zheng D, Jamshidi Y, Greenwood IA. Carr G, et al. Among authors: povstyan ov. Cardiovasc Res. 2016 Nov 1;112(2):581-589. doi: 10.1093/cvr/cvw177. Cardiovasc Res. 2016. PMID: 27389411 Free PMC article.

8

G-protein βγ subunits are positive regulators of Kv7.4 and native vascular Kv7 channel activity.

Stott JB, Povstyan OV, Carr G, Barrese V, Greenwood IA. Stott JB, et al. Among authors: povstyan ov. Proc Natl Acad Sci U S A. 2015 May 19;112(20):6497-502. doi: 10.1073/pnas.1418605112. Epub 2015 May 4. Proc Natl Acad Sci U S A. 2015. PMID: 25941381 Free PMC article.

9

ATP-evoked sustained vasoconstrictions mediated by heteromeric P2X1/4 receptors in cerebral arteries.

Harhun MI, Povstyan OV, Albert AP, Nichols CM. Harhun MI, et al. Among authors: povstyan ov. Stroke. 2014 Aug;45(8):2444-50. doi: 10.1161/STROKEAHA.114.005544. Epub 2014 Jun 24. Stroke. 2014. PMID: 25070962

10

Vasorelaxant effects of novel Kv 7.4 channel enhancers ML213 and NS15370.

Jepps TA, Bentzen BH, Stott JB, Povstyan OV, Sivaloganathan K, Dalby-Brown W, Greenwood IA. Jepps TA, et al. Among authors: povstyan ov. Br J Pharmacol. 2014 Oct;171(19):4413-24. doi: 10.1111/bph.12805. Epub 2014 Aug 14. Br J Pharmacol. 2014. PMID: 24909207 Free PMC article.

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