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Contribution of ATOH1+ Cells to the Homeostasis, Repair, and Tumorigenesis of the Colonic Epithelium.
Ishibashi F, Shimizu H, Nakata T, Fujii S, Suzuki K, Kawamoto A, Anzai S, Kuno R, Nagata S, Ito G, Murano T, Mizutani T, Oshima S, Tsuchiya K, Nakamura T, Watanabe M, Okamoto R. Ishibashi F, et al. Among authors: kuno r. Stem Cell Reports. 2018 Jan 9;10(1):27-42. doi: 10.1016/j.stemcr.2017.11.006. Epub 2017 Dec 7. Stem Cell Reports. 2018. PMID: 29233556 Free PMC article.
Single cell analysis of Crohn's disease patient-derived small intestinal organoids reveals disease activity-dependent modification of stem cell properties.
Suzuki K, Murano T, Shimizu H, Ito G, Nakata T, Fujii S, Ishibashi F, Kawamoto A, Anzai S, Kuno R, Kuwabara K, Takahashi J, Hama M, Nagata S, Hiraguri Y, Takenaka K, Yui S, Tsuchiya K, Nakamura T, Ohtsuka K, Watanabe M, Okamoto R. Suzuki K, et al. Among authors: kuno r. J Gastroenterol. 2018 Sep;53(9):1035-1047. doi: 10.1007/s00535-018-1437-3. Epub 2018 Jan 27. J Gastroenterol. 2018. PMID: 29374777 Free PMC article.
Functional analysis of isoflavones using patient-derived human colonic organoids.
Tsuchiya M, Ito G, Hama M, Nagata S, Kawamoto A, Suzuki K, Shimizu H, Anzai S, Takahashi J, Kuno R, Takeoka S, Hiraguri Y, Sugihara HY, Mizutani T, Yui S, Oshima S, Tsuchiya K, Watanabe M, Okamoto R. Tsuchiya M, et al. Among authors: kuno r. Biochem Biophys Res Commun. 2021 Jan 20;542:40-47. doi: 10.1016/j.bbrc.2021.01.021. Online ahead of print. Biochem Biophys Res Commun. 2021. PMID: 33486190
Notch and TNF-α signaling promote cytoplasmic accumulation of OLFM4 in intestinal epithelium cells and exhibit a cell protective role in the inflamed mucosa of IBD patients.
Kuno R, Ito G, Kawamoto A, Hiraguri Y, Sugihara HY, Takeoka S, Nagata S, Takahashi J, Tsuchiya M, Anzai S, Mizutani T, Shimizu H, Yui S, Oshima S, Tsuchiya K, Watanabe M, Okamoto R. Kuno R, et al. Biochem Biophys Rep. 2021 Jan 11;25:100906. doi: 10.1016/j.bbrep.2020.100906. eCollection 2021 Mar. Biochem Biophys Rep. 2021. PMID: 33490652 Free PMC article.
Ubiquitin D is Upregulated by Synergy of Notch Signalling and TNF-α in the Inflamed Intestinal Epithelia of IBD Patients.
Kawamoto A, Nagata S, Anzai S, Takahashi J, Kawai M, Hama M, Nogawa D, Yamamoto K, Kuno R, Suzuki K, Shimizu H, Hiraguri Y, Yui S, Oshima S, Tsuchiya K, Nakamura T, Ohtsuka K, Kitagawa M, Okamoto R, Watanabe M. Kawamoto A, et al. Among authors: kuno r. J Crohns Colitis. 2019 Mar 30;13(4):495-509. doi: 10.1093/ecco-jcc/jjy180. J Crohns Colitis. 2019. PMID: 30395194
TGF-β promotes fetal gene expression and cell migration velocity in a wound repair model of untransformed intestinal epithelial cells.
Anzai S, Kawamoto A, Nagata S, Takahashi J, Kawai M, Kuno R, Kobayashi S, Watanabe S, Suzuki K, Shimizu H, Hiraguri Y, Takeoka S, Sugihara HY, Yui S, Oshima S, Watanabe M, Okamoto R. Anzai S, et al. Among authors: kuno r. Biochem Biophys Res Commun. 2020 Apr 9;524(3):533-541. doi: 10.1016/j.bbrc.2020.01.108. Epub 2020 Feb 1. Biochem Biophys Res Commun. 2020. PMID: 32014254
Indispensable role of Notch ligand-dependent signaling in the proliferation and stem cell niche maintenance of APC-deficient intestinal tumors.
Nakata T, Shimizu H, Nagata S, Ito G, Fujii S, Suzuki K, Kawamoto A, Ishibashi F, Kuno R, Anzai S, Murano T, Mizutani T, Oshima S, Tsuchiya K, Nakamura T, Hozumi K, Watanabe M, Okamoto R. Nakata T, et al. Among authors: kuno r. Biochem Biophys Res Commun. 2017 Jan 22;482(4):1296-1303. doi: 10.1016/j.bbrc.2016.12.031. Epub 2016 Dec 8. Biochem Biophys Res Commun. 2017. PMID: 27939883
Data showing proliferation and differentiation of intestinal epithelial cells under targeted depletion of Notch ligands in mouse intestine.
Nakata T, Shimizu H, Nagata S, Ito G, Fujii S, Suzuki K, Kawamoto A, Ishibashi F, Kuno R, Anzai S, Murano T, Mizutani T, Oshima S, Tsuchiya K, Nakamura T, Hozumi K, Watanabe M, Okamoto R. Nakata T, et al. Among authors: kuno r. Data Brief. 2016 Dec 29;10:551-556. doi: 10.1016/j.dib.2016.12.045. eCollection 2017 Feb. Data Brief. 2016. PMID: 28124021 Free PMC article.
39 results