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ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis.
Zhang T, Yin C, Fedorov A, Qiao L, Bao H, Beknazarov N, Wang S, Gautam A, Williams RM, Crawford JC, Peri S, Studitsky V, Beg AA, Thomas PG, Walkley C, Xu Y, Poptsova M, Herbert A, Balachandran S. Zhang T, et al. Among authors: balachandran s. Nature. 2022 Jun;606(7914):594-602. doi: 10.1038/s41586-022-04753-7. Epub 2022 May 25. Nature. 2022. PMID: 35614224 Free PMC article.
Targeted Blockade of JAK/STAT3 Signaling Inhibits Ovarian Carcinoma Growth.
Gritsina G, Xiao F, O'Brien SW, Gabbasov R, Maglaty MA, Xu RH, Thapa RJ, Zhou Y, Nicolas E, Litwin S, Balachandran S, Sigal LJ, Huszar D, Connolly DC. Gritsina G, et al. Among authors: balachandran s. Mol Cancer Ther. 2015 Apr;14(4):1035-47. doi: 10.1158/1535-7163.MCT-14-0800. Epub 2015 Feb 2. Mol Cancer Ther. 2015. PMID: 25646015 Free PMC article.
Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast-Driven Nutritional Support and Immunosuppression.
Francescone R, Barbosa Vendramini-Costa D, Franco-Barraza J, Wagner J, Muir A, Lau AN, Gabitova L, Pazina T, Gupta S, Luong T, Rollins D, Malik R, Thapa RJ, Restifo D, Zhou Y, Cai KQ, Hensley HH, Tan Y, Kruger WD, Devarajan K, Balachandran S, Klein-Szanto AJ, Wang H, El-Deiry WS, Vander Heiden MG, Peri S, Campbell KS, Astsaturov I, Cukierman E. Francescone R, et al. Among authors: balachandran s. Cancer Discov. 2021 Feb;11(2):446-479. doi: 10.1158/2159-8290.CD-20-0775. Epub 2020 Oct 30. Cancer Discov. 2021. PMID: 33127842 Free PMC article.
Viral Z-RNA triggers ZBP1-dependent cell death.
Balachandran S, Mocarski ES. Balachandran S, et al. Curr Opin Virol. 2021 Dec;51:134-140. doi: 10.1016/j.coviro.2021.10.004. Epub 2021 Oct 21. Curr Opin Virol. 2021. PMID: 34688984 Free PMC article. Review.
Reovirus Activated Cell Death Pathways.
DeAntoneo C, Danthi P, Balachandran S. DeAntoneo C, et al. Among authors: balachandran s. Cells. 2022 May 27;11(11):1757. doi: 10.3390/cells11111757. Cells. 2022. PMID: 35681452 Free PMC article. Review.
Caspase-8 and FADD prevent spontaneous ZBP1 expression and necroptosis.
Rodriguez DA, Quarato G, Liedmann S, Tummers B, Zhang T, Guy C, Crawford JC, Palacios G, Pelletier S, Kalkavan H, Shaw JJP, Fitzgerald P, Chen MJ, Balachandran S, Green DR. Rodriguez DA, et al. Among authors: balachandran s. Proc Natl Acad Sci U S A. 2022 Oct 11;119(41):e2207240119. doi: 10.1073/pnas.2207240119. Epub 2022 Oct 3. Proc Natl Acad Sci U S A. 2022. PMID: 36191211 Free PMC article.
Detecting Z-RNA and Z-DNA in Mammalian Cells.
Yin C, Zhang T, Balachandran S. Yin C, et al. Among authors: balachandran s. Methods Mol Biol. 2023;2651:277-284. doi: 10.1007/978-1-0716-3084-6_19. Methods Mol Biol. 2023. PMID: 36892774
366 results