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FGFR2b signalling restricts lineage-flexible alveolar progenitors during mouse lung development and converges in mature alveolar type 2 cells.
Jones MR, Lingampally A, Ahmadvand N, Chong L, Wu J, Wilhem J, Vazquez-Armendariz AI, Ansari M, Herold S, Ornitz DM, Schiller HB, Chao CM, Zhang JS, Carraro G, Bellusci S. Jones MR, et al. Among authors: schiller hb. Cell Mol Life Sci. 2022 Nov 29;79(12):609. doi: 10.1007/s00018-022-04626-2. Cell Mol Life Sci. 2022. PMID: 36445537 Free PMC article.
An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics.
Angelidis I, Simon LM, Fernandez IE, Strunz M, Mayr CH, Greiffo FR, Tsitsiridis G, Ansari M, Graf E, Strom TM, Nagendran M, Desai T, Eickelberg O, Mann M, Theis FJ, Schiller HB. Angelidis I, et al. Among authors: schiller hb. Nat Commun. 2019 Feb 27;10(1):963. doi: 10.1038/s41467-019-08831-9. Nat Commun. 2019. PMID: 30814501 Free PMC article.
Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis.
Strunz M, Simon LM, Ansari M, Kathiriya JJ, Angelidis I, Mayr CH, Tsidiridis G, Lange M, Mattner LF, Yee M, Ogar P, Sengupta A, Kukhtevich I, Schneider R, Zhao Z, Voss C, Stoeger T, Neumann JHL, Hilgendorff A, Behr J, O'Reilly M, Lehmann M, Burgstaller G, Königshoff M, Chapman HA, Theis FJ, Schiller HB. Strunz M, et al. Among authors: schiller hb. Nat Commun. 2020 Jul 16;11(1):3559. doi: 10.1038/s41467-020-17358-3. Nat Commun. 2020. PMID: 32678092 Free PMC article.
Inhibition of LTβR signalling activates WNT-induced regeneration in lung.
Conlon TM, John-Schuster G, Heide D, Pfister D, Lehmann M, Hu Y, Ertüz Z, Lopez MA, Ansari M, Strunz M, Mayr C, Angelidis I, Ciminieri C, Costa R, Kohlhepp MS, Guillot A, Günes G, Jeridi A, Funk MC, Beroshvili G, Prokosch S, Hetzer J, Verleden SE, Alsafadi H, Lindner M, Burgstaller G, Becker L, Irmler M, Dudek M, Janzen J, Goffin E, Gosens R, Knolle P, Pirotte B, Stoeger T, Beckers J, Wagner D, Singh I, Theis FJ, de Angelis MH, O'Connor T, Tacke F, Boutros M, Dejardin E, Eickelberg O, Schiller HB, Königshoff M, Heikenwalder M, Yildirim AÖ. Conlon TM, et al. Among authors: schiller hb. Nature. 2020 Dec;588(7836):151-156. doi: 10.1038/s41586-020-2882-8. Epub 2020 Nov 4. Nature. 2020. PMID: 33149305 Free PMC article.
CellRank for directed single-cell fate mapping.
Lange M, Bergen V, Klein M, Setty M, Reuter B, Bakhti M, Lickert H, Ansari M, Schniering J, Schiller HB, Pe'er D, Theis FJ. Lange M, et al. Among authors: schiller hb. Nat Methods. 2022 Feb;19(2):159-170. doi: 10.1038/s41592-021-01346-6. Epub 2022 Jan 13. Nat Methods. 2022. PMID: 35027767 Free PMC article.
Endolysosomal Cation Channels and Lung Disease.
Spix B, Jeridi A, Ansari M, Yildirim AÖ, Schiller HB, Grimm C. Spix B, et al. Among authors: schiller hb. Cells. 2022 Jan 17;11(2):304. doi: 10.3390/cells11020304. Cells. 2022. PMID: 35053420 Free PMC article. Review.
A transcriptomics-guided drug target discovery strategy identifies receptor ligands for lung regeneration.
Wu X, Bos IST, Conlon TM, Ansari M, Verschut V, van der Koog L, Verkleij LA, D'Ambrosi A, Matveyenko A, Schiller HB, Königshoff M, Schmidt M, Kistemaker LEM, Yildirim AÖ, Gosens R. Wu X, et al. Among authors: schiller hb. Sci Adv. 2022 Mar 25;8(12):eabj9949. doi: 10.1126/sciadv.abj9949. Epub 2022 Mar 23. Sci Adv. 2022. PMID: 35319981 Free PMC article.
CD201+ fascia progenitors choreograph injury repair.
Correa-Gallegos D, Ye H, Dasgupta B, Sardogan A, Kadri S, Kandi R, Dai R, Lin Y, Kopplin R, Shenai DS, Wannemacher J, Ichijo R, Jiang D, Strunz M, Ansari M, Angelidis I, Schiller HB, Volz T, Machens HG, Rinkevich Y. Correa-Gallegos D, et al. Among authors: schiller hb. Nature. 2023 Nov;623(7988):792-802. doi: 10.1038/s41586-023-06725-x. Epub 2023 Nov 15. Nature. 2023. PMID: 37968392 Free PMC article.
78 results