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Early diagnosis and treatment of Alzheimer's disease by targeting toxic soluble Aβ oligomers.
Habashi M, Vutla S, Tripathi K, Senapati S, Chauhan PS, Haviv-Chesner A, Richman M, Mohand SA, Dumulon-Perreault V, Mulamreddy R, Okun E, Chill JH, Guérin B, Lubell WD, Rahimipour S. Habashi M, et al. Among authors: okun e. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2210766119. doi: 10.1073/pnas.2210766119. Epub 2022 Nov 28. Proc Natl Acad Sci U S A. 2022. PMID: 36442093 Free PMC article.
Therapeutic B-cell depletion reverses progression of Alzheimer's disease.
Kim K, Wang X, Ragonnaud E, Bodogai M, Illouz T, DeLuca M, McDevitt RA, Gusev F, Okun E, Rogaev E, Biragyn A. Kim K, et al. Among authors: okun e. Nat Commun. 2021 Apr 12;12(1):2185. doi: 10.1038/s41467-021-22479-4. Nat Commun. 2021. PMID: 33846335 Free PMC article.
Physiology and pharmacology of amyloid precursor protein.
Cho Y, Bae HG, Okun E, Arumugam TV, Jo DG. Cho Y, et al. Among authors: okun e. Pharmacol Ther. 2022 Jul;235:108122. doi: 10.1016/j.pharmthera.2022.108122. Epub 2022 Feb 1. Pharmacol Ther. 2022. PMID: 35114285 Review.
Sleeve Gastrectomy Reduces Glycemia but Does Not Affect Cognitive Impairment in Lean 5xFAD Mice.
Samuel I, Ben-Haroush Schyr R, Arad Y, Attali T, Azulai S, Bergel M, Halfon A, Hefetz L, Hirsch T, Israeli H, Lax N, Nitzan K, Sender D, Sweetat S, Okun E, Rosenmann H, Ben-Zvi D. Samuel I, et al. Among authors: okun e. Front Neurosci. 2022 Aug 11;16:937663. doi: 10.3389/fnins.2022.937663. eCollection 2022. Front Neurosci. 2022. PMID: 36033613 Free PMC article.
DNA immunization with HBsAg-based particles expressing a B cell epitope of amyloid β-peptide attenuates disease progression and prolongs survival in a mouse model of Alzheimer's disease.
Olkhanud PB, Mughal M, Ayukawa K, Malchinkhuu E, Bodogai M, Feldman N, Rothman S, Lee JH, Chigurupati S, Okun E, Nagashima K, Mattson MP, Biragyn A. Olkhanud PB, et al. Among authors: okun e. Vaccine. 2012 Feb 21;30(9):1650-8. doi: 10.1016/j.vaccine.2011.12.136. Epub 2012 Jan 14. Vaccine. 2012. PMID: 22248819 Free PMC article.
154 results