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Downregulation of SOCS1 increases interferon-induced ISGylation during differentiation of induced-pluripotent stem cells to hepatocytes.
Edwards JS, Delabat SA, Badilla AD, DiCaprio RC, Hyun J, Burgess RA, Silva T, Dykxhoorn DM, Chen SX, Wang L, Ishida Y, Saito T, Thomas E. Edwards JS, et al. Among authors: dykxhoorn dm. JHEP Rep. 2022 Sep 23;4(12):100592. doi: 10.1016/j.jhepr.2022.100592. eCollection 2022 Dec. JHEP Rep. 2022. PMID: 36439639 Free PMC article.
Generation of an induced pluripotent stem cell line (UMi043-A) from an African American patient with Alzheimer's disease carrying an ABCA7 deletion (p.Arg578Alafs).
Cukier HN, Simon SA, Tang E, Golightly CG, Laverde-Paz MJ, Adams LD, Starks TD, Vance JM, Cuccaro ML, Haines JL, Byrd GS, Pericak-Vance MA, Dykxhoorn DM. Cukier HN, et al. Among authors: dykxhoorn dm. Stem Cell Res. 2024 Apr;76:103364. doi: 10.1016/j.scr.2024.103364. Epub 2024 Feb 25. Stem Cell Res. 2024. PMID: 38422817 Free article.
An Alzheimer's disease risk variant in TTC3 modifies the actin cytoskeleton organization and the PI3K-Akt signaling pathway in iPSC-derived forebrain neurons.
Cukier HN, Duarte CL, Laverde-Paz MJ, Simon SA, Van Booven DJ, Miyares AT, Whitehead PL, Hamilton-Nelson KL, Adams LD, Carney RM, Cuccaro ML, Vance JM, Pericak-Vance MA, Griswold AJ, Dykxhoorn DM. Cukier HN, et al. Among authors: dykxhoorn dm. Neurobiol Aging. 2023 Nov;131:182-195. doi: 10.1016/j.neurobiolaging.2023.07.007. Epub 2023 Jul 17. Neurobiol Aging. 2023. PMID: 37677864 Free article.
HIV Promotes Atherosclerosis via Circulating Extracellular Vesicle MicroRNAs.
Da Fonseca Ferreira A, Wei J, Zhang L, Macon CJ, Degnan B, Jayaweera D, Hare JM, Kolber MA, Bellio M, Khan A, Pan Y, Dykxhoorn DM, Wang L, Dong C. Da Fonseca Ferreira A, et al. Among authors: dykxhoorn dm. Int J Mol Sci. 2023 Apr 20;24(8):7567. doi: 10.3390/ijms24087567. Int J Mol Sci. 2023. PMID: 37108729 Free PMC article.
Anti-amyloid: An antibody to cure Alzheimer's or an attitude.
Osborne OM, Naranjo O, Heckmann BL, Dykxhoorn D, Toborek M. Osborne OM, et al. iScience. 2023 Jul 24;26(8):107461. doi: 10.1016/j.isci.2023.107461. eCollection 2023 Aug 18. iScience. 2023. PMID: 37588168 Free PMC article. Review.
Ancestry-related differences in chromatin accessibility and gene expression of APOE ε4 are associated with Alzheimer's disease risk.
Celis K, Moreno MDMM, Rajabli F, Whitehead P, Hamilton-Nelson K, Dykxhoorn DM, Nuytemans K, Wang L, Flanagan M, Weintraub S, Geula C, Gearing M, Dalgard CL, Jin F, Bennett DA, Schuck T, Pericak-Vance MA, Griswold AJ, Young JI, Vance JM. Celis K, et al. Among authors: dykxhoorn dm. Alzheimers Dement. 2023 Sep;19(9):3902-3915. doi: 10.1002/alz.13075. Epub 2023 Apr 10. Alzheimers Dement. 2023. PMID: 37037656
Brain endothelium-derived extracellular vesicles containing amyloid-beta induce mitochondrial alterations in neural progenitor cells.
Osborne OM, Kowalczyk JM, Louis KDP, Daftari MT, Colbert BM, Naranjo O, Torices S, András IE, Dykxhoorn DM, Toborek M. Osborne OM, et al. Among authors: dykxhoorn dm. Extracell Vesicles Circ Nucl Acids. 2022;3(4):340-362. doi: 10.20517/evcna.2022.22. Epub 2022 Dec 1. Extracell Vesicles Circ Nucl Acids. 2022. PMID: 36649440 Free PMC article.
The natural history and genotype-phenotype correlations of TMPRSS3 hearing loss: an international, multi-center, cohort analysis.
Colbert BM, Lanting C, Smeal M, Blanton S, Dykxhoorn DM, Tang PC, Getchell RL, Velde H, Fehrmann M, Thorpe R, Chapagain P, Elkhaligy H, Kremer H, Yntema H, Haer-Wigman L, Redfield S, Sun T, Bruijn S, Plomp A, Goderie T, van de Kamp J, Free RH, Wassink-Ruiter JK, Widdershoven J, Vanhoutte E, Rotteveel L, Kriek M, van Dooren M, Hoefsloot L, de Gier HHW; DOOFNL Consortium; Schaefer A, Kolbe D, Azaiez H, Rabie G, Aburayyan A, Kawas M, Kanaan M, Holder J, Usami SI, Chen Z, Dai P, Holt J, Nelson R, Choi BY, Shearer E, Smith RJH, Pennings R, Liu XZ. Colbert BM, et al. Among authors: dykxhoorn dm. Hum Genet. 2024 May;143(5):721-734. doi: 10.1007/s00439-024-02648-3. Epub 2024 Apr 30. Hum Genet. 2024. PMID: 38691166 Free PMC article.
92 results