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In vitro evaluation of NA1-115-7-loaded nanoemulsions, an MCL-1-specific inhibitor of natural origin, intended to treat B-cell lymphoproliferative disorders after oral administration.
Séguy L, Daressy F, Lahlil S, Corvaisier S, Dumontet V, Litaudon M, Apel C, Roussi F, Wiels J, Robert A, Groo AC, Malzert-Fréon A. Séguy L, et al. Among authors: robert a. Int J Pharm. 2023 Jan 5;630:122433. doi: 10.1016/j.ijpharm.2022.122433. Epub 2022 Nov 24. Int J Pharm. 2023. PMID: 36436745
Transient stabilization, rather than inhibition, of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma.
Harrington CT, Sotillo E, Robert A, Hayer KE, Bogusz AM, Psathas J, Yu D, Taylor D, Dang CV, Klein PS, Hogarty MD, Geoerger B, El-Deiry WS, Wiels J, Thomas-Tikhonenko A. Harrington CT, et al. Among authors: robert a. Leukemia. 2019 Oct;33(10):2429-2441. doi: 10.1038/s41375-019-0454-4. Epub 2019 Mar 26. Leukemia. 2019. PMID: 30914792 Free PMC article.
Correction: Transient stabilization, rather than inhibition, of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma.
Harrington CT, Sotillo E, Robert A, Hayer KE, Bogusz AM, Psathas J, Yu D, Taylor D, Dang CV, Klein PS, Hogarty MD, Geoerger B, El-Deiry WS, Wiels J, Thomas-Tikhonenko A. Harrington CT, et al. Among authors: robert a. Leukemia. 2020 May;34(5):1485. doi: 10.1038/s41375-019-0650-2. Leukemia. 2020. PMID: 31758088
Drimane Derivatives as the First Examples of Covalent BH3 Mimetics that Target MCL-1.
Daressy F, Malard F, Seguy L, Guérineau V, Apel C, Dumontet V, Robert A, Groo AC, Litaudon M, Bignon J, Desrat S, Malzert-Fréon A, Wiels J, Lescop E, Roussi F. Daressy F, et al. Among authors: robert a. ChemMedChem. 2021 Jun 7;16(11):1788-1797. doi: 10.1002/cmdc.202100011. Epub 2021 Mar 23. ChemMedChem. 2021. PMID: 33665938
1,563 results