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RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes.
Coughlan MT, Thorburn DR, Penfold SA, Laskowski A, Harcourt BE, Sourris KC, Tan AL, Fukami K, Thallas-Bonke V, Nawroth PP, Brownlee M, Bierhaus A, Cooper ME, Forbes JM. Coughlan MT, et al. Among authors: laskowski a. J Am Soc Nephrol. 2009 Apr;20(4):742-52. doi: 10.1681/ASN.2008050514. Epub 2009 Jan 21. J Am Soc Nephrol. 2009. PMID: 19158353 Free PMC article.
Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial Homeostasis.
Coughlan MT, Higgins GC, Nguyen TV, Penfold SA, Thallas-Bonke V, Tan SM, Ramm G, Van Bergen NJ, Henstridge DC, Sourris KC, Harcourt BE, Trounce IA, Robb PM, Laskowski A, McGee SL, Genders AJ, Walder K, Drew BG, Gregorevic P, Qian H, Thomas MC, Jerums G, Macisaac RJ, Skene A, Power DA, Ekinci EI, Wijeyeratne XW, Gallo LA, Herman-Edelstein M, Ryan MT, Cooper ME, Thorburn DR, Forbes JM. Coughlan MT, et al. Among authors: laskowski a. Diabetes. 2016 Apr;65(4):1085-98. doi: 10.2337/db15-0864. Epub 2016 Jan 28. Diabetes. 2016. PMID: 26822084
Complement C5a Induces Renal Injury in Diabetic Kidney Disease by Disrupting Mitochondrial Metabolic Agility.
Tan SM, Ziemann M, Thallas-Bonke V, Snelson M, Kumar V, Laskowski A, Nguyen TV, Huynh K, Clarke MV, Libianto R, Baker ST, Skene A, Power DA, MacIsaac RJ, Henstridge DC, Wetsel RA, El-Osta A, Meikle PJ, Wilson SG, Forbes JM, Cooper ME, Ekinci EI, Woodruff TM, Coughlan MT. Tan SM, et al. Among authors: laskowski a. Diabetes. 2020 Jan;69(1):83-98. doi: 10.2337/db19-0043. Epub 2019 Oct 17. Diabetes. 2020. PMID: 31624141
Targeted deletion of nicotinamide adenine dinucleotide phosphate oxidase 4 from proximal tubules is dispensable for diabetic kidney disease development.
Thallas-Bonke V, Tan SM, Lindblom RS, Snelson M, Granata C, Jha JC, Sourris KC, Laskowski A, Watson A, Tauc M, Rubera I, Zheng G, Shah AM, Harris DCH, Elbatreek MH, Kantharidis P, Cooper ME, Jandeleit-Dahm K, Coughlan MT. Thallas-Bonke V, et al. Among authors: laskowski a. Nephrol Dial Transplant. 2021 May 27;36(6):988-997. doi: 10.1093/ndt/gfaa376. Nephrol Dial Transplant. 2021. PMID: 33367789
SOD2 in skeletal muscle: New insights from an inducible deletion model.
Zhuang A, Yang C, Liu Y, Tan Y, Bond ST, Walker S, Sikora T, Laskowski A, Sharma A, de Haan JB, Meikle PJ, Shimizu T, Coughlan MT, Calkin AC, Drew BG. Zhuang A, et al. Among authors: laskowski a. Redox Biol. 2021 Nov;47:102135. doi: 10.1016/j.redox.2021.102135. Epub 2021 Sep 14. Redox Biol. 2021. PMID: 34598016 Free PMC article.
High-intensity training induces non-stoichiometric changes in the mitochondrial proteome of human skeletal muscle without reorganisation of respiratory chain content.
Granata C, Caruana NJ, Botella J, Jamnick NA, Huynh K, Kuang J, Janssen HA, Reljic B, Mellett NA, Laskowski A, Stait TL, Frazier AE, Coughlan MT, Meikle PJ, Thorburn DR, Stroud DA, Bishop DJ. Granata C, et al. Among authors: laskowski a. Nat Commun. 2021 Dec 3;12(1):7056. doi: 10.1038/s41467-021-27153-3. Nat Commun. 2021. PMID: 34862379 Free PMC article.
72 results