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Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning.
Piel S, Janowska JI, Ward JL, McManus MJ, Jose JS, Starr J, Sheldon M, Clayman CL, Elmér E, Hansson MJ, Jang DH, Karlsson M, Ehinger JK, Kilbaugh TJ. Piel S, et al. Among authors: mcmanus mj. Sci Rep. 2022 Nov 25;12(1):20329. doi: 10.1038/s41598-022-24472-3. Sci Rep. 2022. PMID: 36434021 Free PMC article.
Succinate prodrugs as treatment for acute metabolic crisis during fluoroacetate intoxication in the rat.
Piel S, Janowska JI, Ward JL, McManus MJ, Aronowitz DI, Janowski PK, Starr J, Hook JN, Hefti MM, Clayman CL, Elmér E, Hansson MJ, Jang DH, Karlsson M, Ehinger JK, Kilbaugh TJ. Piel S, et al. Among authors: mcmanus mj. Mol Cell Biochem. 2023 Jun;478(6):1231-1244. doi: 10.1007/s11010-022-04589-9. Epub 2022 Oct 25. Mol Cell Biochem. 2023. PMID: 36282352 Free PMC article.
OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases.
Sturm G, Karan KR, Monzel AS, Santhanam B, Taivassalo T, Bris C, Ware SA, Cross M, Towheed A, Higgins-Chen A, McManus MJ, Cardenas A, Lin J, Epel ES, Rahman S, Vissing J, Grassi B, Levine M, Horvath S, Haller RG, Lenaers G, Wallace DC, St-Onge MP, Tavazoie S, Procaccio V, Kaufman BA, Seifert EL, Hirano M, Picard M. Sturm G, et al. Among authors: mcmanus mj. Commun Biol. 2023 Jan 12;6(1):22. doi: 10.1038/s42003-022-04303-x. Commun Biol. 2023. PMID: 36635485 Free PMC article.
An 18-month-old Girl with a Fleshy Mass in the Ear Canal.
Li Y, Huang SJ, McManus MJ. Li Y, et al. Among authors: mcmanus mj. Pediatr Rev. 2021 Jan;42(Suppl 1):S1-S3. doi: 10.1542/pir.2018-0325. Pediatr Rev. 2021. PMID: 33386348 No abstract available.
Oxygen Exposure During Cardiopulmonary Resuscitation Is Associated With Cerebral Oxidative Injury in a Randomized, Blinded, Controlled, Preclinical Trial.
Marquez AM, Morgan RW, Ko T, Landis WP, Hefti MM, Mavroudis CD, McManus MJ, Karlsson M, Starr J, Roberts AL, Lin Y, Nadkarni V, Licht DJ, Berg RA, Sutton RM, Kilbaugh TJ. Marquez AM, et al. Among authors: mcmanus mj. J Am Heart Assoc. 2020 May 5;9(9):e015032. doi: 10.1161/JAHA.119.015032. Epub 2020 Apr 23. J Am Heart Assoc. 2020. PMID: 32321350 Free PMC article.
51 results