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CSF tau microtubule-binding region identifies pathological changes in primary tauopathies.
Horie K, Barthélemy NR, Spina S, VandeVrede L, He Y, Paterson RW, Wright BA, Day GS, Davis AA, Karch CM, Seeley WW, Perrin RJ, Koppisetti RK, Shaikh F, Lago AL, Heuer HW, Ghoshal N, Gabelle A, Miller BL, Boxer AL, Bateman RJ, Sato C. Horie K, et al. Among authors: bateman rj. Nat Med. 2022 Dec;28(12):2547-2554. doi: 10.1038/s41591-022-02075-9. Epub 2022 Nov 24. Nat Med. 2022. PMID: 36424467 Free PMC article.
Neuropathologic assessment of participants in two multi-center longitudinal observational studies: the Alzheimer Disease Neuroimaging Initiative (ADNI) and the Dominantly Inherited Alzheimer Network (DIAN).
Cairns NJ, Perrin RJ, Franklin EE, Carter D, Vincent B, Xie M, Bateman RJ, Benzinger T, Friedrichsen K, Brooks WS, Halliday GM, McLean C, Ghetti B, Morris JC; Alzheimer Disease Neuroimaging Initiative; Dominantly Inherited Alzheimer Network. Cairns NJ, et al. Among authors: bateman rj. Neuropathology. 2015 Aug;35(4):390-400. doi: 10.1111/neup.12205. Epub 2015 May 12. Neuropathology. 2015. PMID: 25964057 Free PMC article.
Tau Kinetics in Neurons and the Human Central Nervous System.
Sato C, Barthélemy NR, Mawuenyega KG, Patterson BW, Gordon BA, Jockel-Balsarotti J, Sullivan M, Crisp MJ, Kasten T, Kirmess KM, Kanaan NM, Yarasheski KE, Baker-Nigh A, Benzinger TLS, Miller TM, Karch CM, Bateman RJ. Sato C, et al. Among authors: bateman rj. Neuron. 2018 Mar 21;97(6):1284-1298.e7. doi: 10.1016/j.neuron.2018.02.015. Neuron. 2018. PMID: 29566794 Free PMC article.
Tau Kinetics in Neurons and the Human Central Nervous System.
Sato C, Barthélemy NR, Mawuenyega KG, Patterson BW, Gordon BA, Jockel-Balsarotti J, Sullivan M, Crisp MJ, Kasten T, Kirmess KM, Kanaan NM, Yarasheski KE, Baker-Nigh A, Benzinger TLS, Miller TM, Karch CM, Bateman RJ. Sato C, et al. Among authors: bateman rj. Neuron. 2018 May 16;98(4):861-864. doi: 10.1016/j.neuron.2018.04.035. Neuron. 2018. PMID: 29772204 Free PMC article. No abstract available.
Genetic variants associated with Alzheimer's disease confer different cerebral cortex cell-type population structure.
Li Z, Del-Aguila JL, Dube U, Budde J, Martinez R, Black K, Xiao Q, Cairns NJ; Dominantly Inherited Alzheimer Network (DIAN); Dougherty JD, Lee JM, Morris JC, Bateman RJ, Karch CM, Cruchaga C, Harari O. Li Z, et al. Among authors: bateman rj. Genome Med. 2018 Jun 8;10(1):43. doi: 10.1186/s13073-018-0551-4. Genome Med. 2018. PMID: 29880032 Free PMC article.
Discovery and validation of autosomal dominant Alzheimer's disease mutations.
Hsu S, Gordon BA, Hornbeck R, Norton JB, Levitch D, Louden A, Ziegemeier E, Laforce R Jr, Chhatwal J, Day GS, McDade E, Morris JC, Fagan AM, Benzinger TLS, Goate AM, Cruchaga C, Bateman RJ; Dominantly Inherited Alzheimer Network (DIAN); Karch CM. Hsu S, et al. Among authors: bateman rj. Alzheimers Res Ther. 2018 Jul 18;10(1):67. doi: 10.1186/s13195-018-0392-9. Alzheimers Res Ther. 2018. PMID: 30021643 Free PMC article.
CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline.
Suárez-Calvet M, Capell A, Araque Caballero MÁ, Morenas-Rodríguez E, Fellerer K, Franzmeier N, Kleinberger G, Eren E, Deming Y, Piccio L, Karch CM, Cruchaga C, Paumier K, Bateman RJ, Fagan AM, Morris JC, Levin J, Danek A, Jucker M, Masters CL, Rossor MN, Ringman JM, Shaw LM, Trojanowski JQ, Weiner M, Ewers M, Haass C; Dominantly Inherited Alzheimer Network; Alzheimer's Disease Neuroimaging Initiative. Suárez-Calvet M, et al. Among authors: bateman rj. EMBO Mol Med. 2018 Dec;10(12):e9712. doi: 10.15252/emmm.201809712. EMBO Mol Med. 2018. PMID: 30482868 Free PMC article.
Protein production is an early biomarker for RNA-targeted therapies.
Self WK, Schoch KM, Alex J, Barthélemy N, Bollinger JG, Sato C, Cole T, Kordasiewicz HB, Swayze E, Bateman RJ, Miller TM. Self WK, et al. Among authors: bateman rj. Ann Clin Transl Neurol. 2018 Oct 14;5(12):1492-1504. doi: 10.1002/acn3.657. eCollection 2018 Dec. Ann Clin Transl Neurol. 2018. PMID: 30564616 Free PMC article.
Tau Phosphorylation Rates Measured by Mass Spectrometry Differ in the Intracellular Brain vs. Extracellular Cerebrospinal Fluid Compartments and Are Differentially Affected by Alzheimer's Disease.
Barthélemy NR, Mallipeddi N, Moiseyev P, Sato C, Bateman RJ. Barthélemy NR, et al. Among authors: bateman rj. Front Aging Neurosci. 2019 May 21;11:121. doi: 10.3389/fnagi.2019.00121. eCollection 2019. Front Aging Neurosci. 2019. PMID: 31178717 Free PMC article.
SILK studies - capturing the turnover of proteins linked to neurodegenerative diseases.
Paterson RW, Gabelle A, Lucey BP, Barthélemy NR, Leckey CA, Hirtz C, Lehmann S, Sato C, Patterson BW, West T, Yarasheski K, Rohrer JD, Wildburger NC, Schott JM, Karch CM, Wray S, Miller TM, Elbert DL, Zetterberg H, Fox NC, Bateman RJ. Paterson RW, et al. Among authors: bateman rj. Nat Rev Neurol. 2019 Jul;15(7):419-427. doi: 10.1038/s41582-019-0222-0. Epub 2019 Jun 20. Nat Rev Neurol. 2019. PMID: 31222062 Free PMC article. Review.
296 results