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Protein aggregation and calcium dysregulation are hallmarks of familial Parkinson's disease in midbrain dopaminergic neurons.
Virdi GS, Choi ML, Evans JR, Yao Z, Athauda D, Strohbuecker S, Nirujogi RS, Wernick AI, Pelegrina-Hidalgo N, Leighton C, Saleeb RS, Kopach O, Alrashidi H, Melandri D, Perez-Lloret J, Angelova PR, Sylantyev S, Eaton S, Heales S, Rusakov DA, Alessi DR, Kunath T, Horrocks MH, Abramov AY, Patani R, Gandhi S. Virdi GS, et al. Among authors: patani r. NPJ Parkinsons Dis. 2022 Nov 24;8(1):162. doi: 10.1038/s41531-022-00423-7. NPJ Parkinsons Dis. 2022. PMID: 36424392 Free PMC article.
Characterizing the RNA targets and position-dependent splicing regulation by TDP-43.
Tollervey JR, Curk T, Rogelj B, Briese M, Cereda M, Kayikci M, König J, Hortobágyi T, Nishimura AL, Zupunski V, Patani R, Chandran S, Rot G, Zupan B, Shaw CE, Ule J. Tollervey JR, et al. Among authors: patani r. Nat Neurosci. 2011 Apr;14(4):452-8. doi: 10.1038/nn.2778. Epub 2011 Feb 27. Nat Neurosci. 2011. PMID: 21358640 Free PMC article.
Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning.
Bell KF, Al-Mubarak B, Fowler JH, Baxter PS, Gupta K, Tsujita T, Chowdhry S, Patani R, Chandran S, Horsburgh K, Hayes JD, Hardingham GE. Bell KF, et al. Among authors: patani r. Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):E1-2; author reply E3-4. doi: 10.1073/iti0111108. Epub 2010 Dec 21. Proc Natl Acad Sci U S A. 2011. PMID: 21177433 Free PMC article. No abstract available.
Flexor hallucis brevis spasm.
Patani R, Muhammed N, Chaudhuri A. Patani R, et al. Muscle Nerve. 2013 Jun;47(6):939. doi: 10.1002/mus.23796. Epub 2013 Mar 26. Muscle Nerve. 2013. PMID: 23532972 No abstract available.
Abnormal tau phosphorylation in primary progressive multiple sclerosis.
Anderson JM, Patani R, Reynolds R, Nicholas R, Compston A, Spillantini MG, Chandran S. Anderson JM, et al. Among authors: patani r. Acta Neuropathol. 2010 May;119(5):591-600. doi: 10.1007/s00401-010-0671-4. Epub 2010 Mar 21. Acta Neuropathol. 2010. PMID: 20306268
93 results