Heales S - Search Results

1

Protein aggregation and calcium dysregulation are hallmarks of familial Parkinson's disease in midbrain dopaminergic neurons.

Virdi GS, Choi ML, Evans JR, Yao Z, Athauda D, Strohbuecker S, Nirujogi RS, Wernick AI, Pelegrina-Hidalgo N, Leighton C, Saleeb RS, Kopach O, Alrashidi H, Melandri D, Perez-Lloret J, Angelova PR, Sylantyev S, Eaton S, Heales S, Rusakov DA, Alessi DR, Kunath T, Horrocks MH, Abramov AY, Patani R, Gandhi S. Virdi GS, et al. Among authors: heales s. NPJ Parkinsons Dis. 2022 Nov 24;8(1):162. doi: 10.1038/s41531-022-00423-7. NPJ Parkinsons Dis. 2022. PMID: 36424392 Free PMC article.

2

Determination of coenzyme Q10 status in blood mononuclear cells, skeletal muscle, and plasma by HPLC with di-propoxy-coenzyme Q10 as an internal standard.

Duncan AJ, Heales SJ, Mills K, Eaton S, Land JM, Hargreaves IP. Duncan AJ, et al. Among authors: heales sj. Clin Chem. 2005 Dec;51(12):2380-2. doi: 10.1373/clinchem.2005.054643. Clin Chem. 2005. PMID: 16306103 No abstract available.

3

Microglial neurotransmitter receptors trigger superoxide production in microglia; consequences for microglial-neuronal interactions.

Mead EL, Mosley A, Eaton S, Dobson L, Heales SJ, Pocock JM. Mead EL, et al. Among authors: heales sj. J Neurochem. 2012 Apr;121(2):287-301. doi: 10.1111/j.1471-4159.2012.07659.x. Epub 2012 Mar 13. J Neurochem. 2012. PMID: 22243365 Free article.

4

Human neuronal coenzyme Q10 deficiency results in global loss of mitochondrial respiratory chain activity, increased mitochondrial oxidative stress and reversal of ATP synthase activity: implications for pathogenesis and treatment.

Duberley KE, Abramov AY, Chalasani A, Heales SJ, Rahman S, Hargreaves IP. Duberley KE, et al. Among authors: heales sj. J Inherit Metab Dis. 2013 Jan;36(1):63-73. doi: 10.1007/s10545-012-9511-0. Epub 2012 Jul 6. J Inherit Metab Dis. 2013. PMID: 22767283

5

Coenzyme Q10 quantification in muscle, fibroblasts and cerebrospinal fluid by liquid chromatography/tandem mass spectrometry using a novel deuterated internal standard.

Duberley KE, Hargreaves IP, Chaiwatanasirikul KA, Heales SJ, Land JM, Rahman S, Mills K, Eaton S. Duberley KE, et al. Among authors: heales sj. Rapid Commun Mass Spectrom. 2013 May 15;27(9):924-30. doi: 10.1002/rcm.6529. Rapid Commun Mass Spectrom. 2013. PMID: 23592193

6

Levels of 5-methyltetrahydrofolate and ascorbic acid in cerebrospinal fluid are correlated: implications for the accelerated degradation of folate by reactive oxygen species.

Aylett SB, Neergheen V, Hargreaves IP, Eaton S, Land JM, Rahman S, Heales SJ. Aylett SB, et al. Among authors: heales sj. Neurochem Int. 2013 Dec;63(8):750-5. doi: 10.1016/j.neuint.2013.10.002. Epub 2013 Oct 15. Neurochem Int. 2013. PMID: 24140430

7

Effect of Coenzyme Q10 supplementation on mitochondrial electron transport chain activity and mitochondrial oxidative stress in Coenzyme Q10 deficient human neuronal cells.

Duberley KE, Heales SJ, Abramov AY, Chalasani A, Land JM, Rahman S, Hargreaves IP. Duberley KE, et al. Among authors: heales sj. Int J Biochem Cell Biol. 2014 May;50:60-3. doi: 10.1016/j.biocel.2014.02.003. Epub 2014 Feb 15. Int J Biochem Cell Biol. 2014. PMID: 24534273

8

Inhibition of neuronal mitochondrial complex I or lysosomal glucocerebrosidase is associated with increased dopamine and serotonin turnover.

de la Fuente C, Burke DG, Eaton S, Heales SJR. de la Fuente C, et al. Among authors: heales sjr. Neurochem Int. 2017 Oct;109:94-100. doi: 10.1016/j.neuint.2017.02.013. Epub 2017 Feb 24. Neurochem Int. 2017. PMID: 28242245

9

Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders.

Augustin K, Khabbush A, Williams S, Eaton S, Orford M, Cross JH, Heales SJR, Walker MC, Williams RSB. Augustin K, et al. Among authors: heales sjr. Lancet Neurol. 2018 Jan;17(1):84-93. doi: 10.1016/S1474-4422(17)30408-8. Epub 2017 Dec 16. Lancet Neurol. 2018. PMID: 29263011 Review.

10

Expression of mutant exon 1 huntingtin fragments in human neural stem cells and neurons causes inclusion formation and mitochondrial dysfunction.

Ghosh R, Wood-Kaczmar A, Dobson L, Smith EJ, Sirinathsinghji EC, Kriston-Vizi J, Hargreaves IP, Heaton R, Herrmann F, Abramov AY, Lam AJ, Heales SJ, Ketteler R, Bates GP, Andre R, Tabrizi SJ. Ghosh R, et al. FASEB J. 2020 Jun;34(6):8139-8154. doi: 10.1096/fj.201902277RR. Epub 2020 Apr 23. FASEB J. 2020. PMID: 32329133 Free PMC article.

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