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CDKL5 deficiency causes epileptic seizures independent of cellular mosaicism.
Takahashi S, Takeguchi R, Tanaka R, Fukuoka M, Koike T, Ohtani H, Inoue K, Fukuda M, Kurahashi H, Nakamura K, Tominaga K, Matsubayashi T, Itoh M, Tanaka T. Takahashi S, et al. Among authors: tanaka t, tanaka r. J Neurol Sci. 2022 Dec 15;443:120498. doi: 10.1016/j.jns.2022.120498. Epub 2022 Nov 16. J Neurol Sci. 2022. PMID: 36417806
CDKL5 controls postsynaptic localization of GluN2B-containing NMDA receptors in the hippocampus and regulates seizure susceptibility.
Okuda K, Kobayashi S, Fukaya M, Watanabe A, Murakami T, Hagiwara M, Sato T, Ueno H, Ogonuki N, Komano-Inoue S, Manabe H, Yamaguchi M, Ogura A, Asahara H, Sakagami H, Mizuguchi M, Manabe T, Tanaka T. Okuda K, et al. Among authors: tanaka t. Neurobiol Dis. 2017 Oct;106:158-170. doi: 10.1016/j.nbd.2017.07.002. Epub 2017 Jul 6. Neurobiol Dis. 2017. PMID: 28688852
Comprehensive behavioral analysis of the Cdkl5 knockout mice revealed significant enhancement in anxiety- and fear-related behaviors and impairment in both acquisition and long-term retention of spatial reference memory.
Okuda K, Takao K, Watanabe A, Miyakawa T, Mizuguchi M, Tanaka T. Okuda K, et al. Among authors: tanaka t. PLoS One. 2018 Apr 27;13(4):e0196587. doi: 10.1371/journal.pone.0196587. eCollection 2018. PLoS One. 2018. PMID: 29702698 Free PMC article.
Fused Aromatic and Antiaromatic Smaragdyrin Dimers.
Liu Y, Tanaka T, Shimizu D, Rao Y, Xu L, Yin B, Zhou M, Song J, Osuka A. Liu Y, et al. Among authors: tanaka t. Angew Chem Int Ed Engl. 2024 Jun 3:e202408478. doi: 10.1002/anie.202408478. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 38829748
Clonal evolution of hematopoietic stem cells after cancer chemotherapy.
Uryu H, Saeki K, Haeno H, Kapadia CD, Furudate K, Nangalia J, Chapman MS, Zhao L, Hsu JI, Zhao C, Chen S, Tanaka T, Li Z, Yang H, DiNardo C, Daver N, Pemmaraju N, Jain N, Ravandi F, Zhang J, Song X, Thompson E, Tang H, Little L, Gumbs C, Orlowski RZ, Qazilbash M, Bhalla K, Colla S, Kantarjian H, Shamanna RK, Ramos CB, Nakada D, Futreal PA, Shpall E, Goodell M, Garcia-Manero G, Takahashi K. Uryu H, et al. Among authors: tanaka t. bioRxiv [Preprint]. 2024 May 24:2024.05.23.595594. doi: 10.1101/2024.05.23.595594. bioRxiv. 2024. PMID: 38826462 Free PMC article. Preprint.
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