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The free fatty acid-binding pocket is a conserved hallmark in pathogenic β-coronavirus spike proteins from SARS-CoV to Omicron.
Toelzer C, Gupta K, Yadav SKN, Hodgson L, Williamson MK, Buzas D, Borucu U, Powers K, Stenner R, Vasileiou K, Garzoni F, Fitzgerald D, Payré C, Gautam G, Lambeau G, Davidson AD, Verkade P, Frank M, Berger I, Schaffitzel C. Toelzer C, et al. Among authors: gupta k. Sci Adv. 2022 Nov 25;8(47):eadc9179. doi: 10.1126/sciadv.adc9179. Epub 2022 Nov 23. Sci Adv. 2022. PMID: 36417532 Free PMC article.
Zooming in on Transcription Preinitiation.
Gupta K, Sari-Ak D, Haffke M, Trowitzsch S, Berger I. Gupta K, et al. J Mol Biol. 2016 Jun 19;428(12):2581-2591. doi: 10.1016/j.jmb.2016.04.003. Epub 2016 Apr 8. J Mol Biol. 2016. PMID: 27067110 Free PMC article. Review.
Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein.
Toelzer C, Gupta K, Yadav SKN, Borucu U, Davidson AD, Kavanagh Williamson M, Shoemark DK, Garzoni F, Staufer O, Milligan R, Capin J, Mulholland AJ, Spatz J, Fitzgerald D, Berger I, Schaffitzel C. Toelzer C, et al. Among authors: gupta k. Science. 2020 Nov 6;370(6517):725-730. doi: 10.1126/science.abd3255. Epub 2020 Sep 21. Science. 2020. PMID: 32958580 Free PMC article.
4,195 results